سطح سرمی ویتامین د به عنوان نشانه ای از کاهش ویتامین در جریان درمان ضد سل

حبیب زاده, شهرام ، قاسمی, احمد ، سلیمانی, نوا ، باقربندی, سعيده ، پورمحمد جان, ناهید (1392) سطح سرمی ویتامین د به عنوان نشانه ای از کاهش ویتامین در جریان درمان ضد سل. Archives of Clinical Infectious Diseases ــ 8 (3). e18271. شاپا 2641-2345

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آدرس اینترنتی رسمی : http://archcid.com/?page=article&article_id=18271

عنوان انگليسي

Serum Parathormone Levels as a Sign for Vitamin D Deficiency During Antiuberculosis Therapy, a Pilot Study- Tuberculosis Therapy, a Pilot Study

خلاصه انگلیسی

Background: Vitamin D (Vit D) level may change variously in serums of patients undergoing anti-tuberculosis (anti-TB) therapy using antibiotics such as isoniazid and rifampin. Objectives: The current study aimed to evaluate all components of calcium (Ca) regulatory agents in the six- month period of standard anti- TB therapy. Patients and Methods: Eight adults whose pulmonary TB had been diagnosed with positive sputum test were selected for the study. For each patient Ca, phosphate (P), albumin (Alb), alkaline phosphatase (ALP), Vit D (25 OH), parathormone (PTH) levels were checked before and after drug therapy monthly, until treatment termination. Verbal informed consent was obtained from the patients and they were free to leave the study at any time without any restrictions, and did not have to pay for the tests. Results: Vit D levels decreased significantly after three months (P < 0.05). On the other hand, serum levels of Alb significantly increased, probably due to improved appetite in all of the checking times (P = 0.001). Serum levels of PTH also increased, but not significantly. Conclusions: Considering the decreasing levels of Vit D during anti-TB therapy, it seems reasonable to monitor serum Ca, Vit D and PTH levels in patients during the anti-TB therapy especially in patients that Vit D deficiency is more probable.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :شهرام حبیب زاده
نویسنده مسئول :ناهید پورمحمد جان
اطلاعات اضافی :indexed in: CABI , Index Medicus for the WHO Eastern Mediterranean Region (IMEMR) , Index Copernicus , Islamic World Science Citation (ISC) , DOAJ , SID , IranMedex , Magiran , Google Scholar
کلید واژه ها (انگلیسی):Vitamin D ; Anti-Tubercular Agents ; Parathormone
موضوعات :QV فارماکولوژی
WC بیماریهای واگیر
WK سیستم غدد
بخش های دانشگاهی :دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :5548
ارائه شده توسط : دکتر شهرام حبیب زاده
ارائه شده در تاریخ :17 فروردین 1393 10:23
آخرین تغییر :17 فروردین 1393 10:23

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