فعالیت احتلامی(جنسی) عصاره آبی دانه گرده خرمای نر در رتهای نر

عابدی, علی and پرویز, محسن and کریمیان, سید مرتضی and صادقی پور رودسری, حمید رضا (1391) فعالیت احتلامی(جنسی) عصاره آبی دانه گرده خرمای نر در رتهای نر. Advances in Sexual Medicine ــ 3 (1). pp. 28-34. شاپا 2164-5191

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Official URL: http://www.scirp.org/Journal/Home.aspx?IssueID=253...


Aphrodisiac Activity of Aqueous Extract of Phoenix dactylifera Pollen in Male Rats

English Abstract

Aim of study: Ancient literature alluded to the use of a number of plants/preparations as sex enhancer. One of such botanicals is Phoenix dactylifera in which the pollen grain has been acclaimed to be used as an aphrodisiac. However, the validity has not been scientifically tested. Dopamine is known to facilitate male sexual function. Therefore, the present study was undertaken to evaluate the effect of aqueous extract of Phoenix dactylifera pollen on the sexual behavior of male rats and to measure of serum Estradiol and Testostrone. Also, dopamine transmission in the nucleus accumbence (NAc) was studied in male rats using in vivo microdialysis. Methods and Materials: sixty male rats were randomized into 6 groups (A-F). Group A received 0.2 ml of Normal Saline mixed with Dimethyl Sulphate (DMSO), while groups B-F were injected same volume containing 35 mg/kg, 70 mg/kg, 105 mg/kg, 140 mg/kg and 350 mg/kg of DPP extract, respectively. Sexual behavioral parameters including mounting, intromission and ejaculation frequencies and latencies were recorded in male rats one hour after injection of extract by mating with a receptive female (1:1). The male serum testosterone and estradiol concentrations were also determined. Results: All doses stimulated male sexual behavior. Extract significantly increased mount, ejaculation, intromission frequencies and ejaculation latency in comparison to controlled ones (p < 0.001). Mount and intromission latencies significantly reduced (p < 0.001). Maximum effect was observed in dose 140 mg/kg. This extract was found to enhance Testestrone, Estradiol and the orientation of males toward female ones by increasing mounting and ano-genital investigatory behavior. Conclusions: Data from this study identified that the aqueous extract of Phoenix dactylifera pollen grain enhanced sexual behaviour in male rats. The improved sexual appetitive behaviour in male rats may be attributed, to the alkaloids, saponins, and or flavonoids since these phytochemicals has engorgement, androgen enhancing. Also, our findings support the traditional use of this plant as acclaimed aphrodisiac and for the treatment of pre-ejaculation and impotency.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :علی عابدی
نویسنده :محسن پرویز
نویسنده :سید مرتضی کریمیان
نویسنده مسئول :حمید رضا صادقی پور رودسری
Additional Information:indexed in: Google Scholar , Academic Keys , Academic OneFile , AiritiLibrary , CNKI SCHOLAR , Gale , Health Reference Center Academic , JournalSeek , JournalTOCs National Library of Australia , Open Science Directory , Proquest , SHERPA/RoMEO , Standard Periodical Directory(Mediafinder) , Ulrich, Universe Digital Library(UDL), Worldcat , Zeitschriftendatenbank (ZDB)
Uncontrolled Keywords:دانه گرده خرمای نر، عصاره آبی، رت نر، رفتار جنسی، زود انزالی،
کلیدواژه ها (انگلیسی):Aphrodisiac Activity; Microdialysis; Dopamine; Testostrone; Estradiol; Male Rat; Phoenix dactylifera Pollen Grain; Pre-Ejaculation; Sexual Behavior
Subjects:QT physiology
WK Endocrine System
WL Nervous system
WT Geriatrics . Chronic Diseases
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of physiology
ID Code:5567
Deposited By: Dr ALI ABEDI
Deposited On:26 Jan 1393 09:24
Last Modified:26 Jan 1393 09:24

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