title

ارزیابی اضافه کردن هیالورونیداز به تریامسینولون در تزریق اپیدورال ترانس فورامینال تحت گاید فلوروسکپی در رادیکولوپاتی کمری

ایمانی, فرناد and رحیم زاده, پوپک and انتظاری, سعید رضا and محمدیان اردی, علی and منصوری, تیام (1389) ارزیابی اضافه کردن هیالورونیداز به تریامسینولون در تزریق اپیدورال ترانس فورامینال تحت گاید فلوروسکپی در رادیکولوپاتی کمری. در: The First International Congress of Regional Anesthesia and Pain Interventions, September 15- 17 , 2010, Olympic Hotel, Tehran , iran.

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EVALUATION OF ADDING HYALURONIDASE TO TRIAMCINOLONE IN FLUOROSCOPICALLY GUIDED TRANSFORAMINAL EPIDURAL INJECTION FOR LUMBAR RADICULOPATHY

English Abstract

Background and aims: Epidural steroids injections such as triamcinolone and dexamethasone by transforaminal or interlaminar approaches are commonly used for the treatment of radicular symptoms with various degree of success. The aim of this study was evaluation the effects of adding hyaluronidase to triamcinolone in fluoroscopically guided transforaminal epidural injection in patients with failed back surgery syndrome (FBSS). Methods: In a double blinded RCT study, 25 patient with lumbar radiculopathy due to failed back surgery syndrome (FBSS) who candidated for fluoroscopically guided transforaminal epidural injection, were randomly allocated into T (triamcinolone) and HT (hyaluronidase and triamcinolone) groups. The procedure was performed in the interventional pain operation room, Rasoul-Akram Hospital, under aseptic conditions and with blunt curved needle. After injection of contrast media and correct needle placement in T group, bupivacaine 0.5% (1ml), triamcinolone (40mg), hypertonic saline 5% (1ml) and normal saline (1ml) was injected per each nerve root. In HT group, hyaluronidase (1500IU) was administrered instead of normal saline. Patients were evaluated in recovery room and in 1, 2, and 4 weeks later considering pain score, satisfaction and neurological examinations. In the case of pain, using celecoxib 100mg was advocated. Results: Pain relief and patient satisfaction were significantly higher in HT group and total analgesic consumption was statistically lower in HT group that T group (p<0.05). Effectiveness of technique (more than 50% pain relief) was statistically meaningful 2 weeks after performance in HT group. Conclusion: Our data suggest addition of hyaluronidase to triamcinolone for transforaminal epidural injection, in patient with lumbar radiculopathy due to FBSS causes more pain relief without any complications

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده اول :فرناد ایمانی
نویسنده :پوپک رحیم زاده
نویسنده :سعید رضا انتظاری
نویسنده :علی محمدیان اردی
نویسنده :تیام منصوری
کلیدواژه ها (انگلیسی):HYALURONIDASE , EPIDURAL , LUMBAR RADICULOPATHY
Subjects:QV pharmacology
WE Musculoskeletal system
WL Nervous system
WT Geriatrics . Chronic Diseases
Divisions:Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
ID Code:5579
Deposited By: Dr Ali Mohammadian
Deposited On:28 Jan 1393 12:17
Last Modified:28 Jan 1393 12:17

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