ارتباط سازگاری پیش از بیماری و عملکرد عمومی زمان بستری و شدت مانیا، در پیگیری 3 ماهه در درمان کودکان و نوجوانان مبتلا به اختلال دوقطبی

عنوان انگليسی

Premorbid Adjustment, General Performance in Time of Hospitalizing and Mania Severity in 3 Month Follow up in Treatment of Children and Adolescents with Bipolar Disorder

خلاصه انگلیسی

Introduction: The therapeutic outcome of children’s and adolescents’ bipolar disorder was affected by many factors, two of which are premorbid adjustment and patient general performance in time of hospitalization. Objectives: The aim of this study was to investigate the role of premorbid adjustment and patient general performance in hospitalizing time in the prediction of mania severity in 3 month follow up in children and adolescents with bipolar disorder. Methods: The participants were 80 patients under 18 (10-18 year old) in during January 2009 to July 2010, who were admitted to Tehran Roozbeh Hospital with a diagnosis of bipolar disorder. The available sampling method was used for selection. The design of the study was prospective Cohort. Participants were evaluated using a researcher made questionnaire, K-SADS (to confirm the diagnosis), YMRS, CGAS and PAS at admission, discharge, and 3-month follow-up. For data analysis, Pearson Correlation coefficient and multivariate regressions analysis were used. Results: The results of Pearson correlation test showed that patients’ general performance in time of hospitalizing was negatively correlated with severity of mania in the 3 -month follow up. The result of regression test showed that this variable explains 7 percent of variance of severity of mania in the 3- month follows up. Results of this study did not show any relationship between severity of mania and premorbid adjustment. Conclusion: These results point the importance of patients’ general performance in therapeutic decisions in bipolar disorder.

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