مطالعه تاثیر اسفناج بر استرس اکسیداتیو ناشی از ورزش

بهلولی, شهاب and برمکی, سارا and خوش خواهش, فائقه and نخستین روحی, بابک (1394) مطالعه تاثیر اسفناج بر استرس اکسیداتیو ناشی از ورزش. The Journal of sports medicine and physical fitness ــ 55 (6). pp. 609-614. شاپا 4707-0022

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The effect of spinach supplementation on exercise-induced oxidative stress.

English Abstract

AIM Nutritional supplements have been very popular among athletes and individuals. Spinach is an important dietary vegetable rich in antioxidants which is commonly consumed. This study was conducted to assess the effects of chronic daily spinach supplementation on known markers of oxidative stress and muscle damage following half-marathonin well-trained healthy young men. METHODS Twenty well-trained men volunteered for this study. Participants were randomized in an open study placebo-controlled fashion into two groups: Spinach (S) (n = 10) and placebo (P) (n =10). The participants took spinach supplementation or placebo daily for 14 days before running.Participants ran 21.1 km. The spinach supplementation was prepared at 1g/kg body weight. Total Antioxidant Capacity (TAC) was determined as marker of plasma antioxidant capacity. Creatinekinase (CK) was measured as marker of muscle damage and malondialdehyde (MDA), protein carbonyl (PC) and uric acid were measured as markers of oxidative stress. RESULTS TAC significantly elevated after supplementation in S group (P < 0.05). Acute exercise led to elevated levels of serum MDA, PC, and CK (P < 0.05). Spinach supplementation maintained PC, MDA, uric acid, and CK at lower levels after exercise than the placebo (P < 0.05). CONCLUSION These results suggest that chronic daily oral supplementation of spinach has alleviating effects on known markers of oxidative stress and muscle damage following a half-marathon in well trained healthy young men.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :شهاب بهلولی
نویسنده :سارا برمکی
نویسنده :فائقه خوش خواهش
نویسنده مسئول :بابک نخستین روحی
Additional Information:Impact Factor: (2014): 0.972 Indexed in: ISI, Chemical Abstracts, Pubmed\medline\ index medicus, EMBASE, CINAHL, Current Contents
Uncontrolled Keywords:اسفناج، آنتی اکسیدان تام، مالون دی آلدهید، پروتئین کربونیل شده ، کراتینین کیناز
کلیدواژه ها (انگلیسی):Spinach, TAC, Malondialdehyde, protein carbonylation, CK
Subjects:QT physiology
QV pharmacology
Divisions:School of Pharmacy > Department of Pharmacology
ID Code:5787
Deposited By: Dr Shahab Bohlooli
Deposited On:23 Jul 1394 07:45
Last Modified:23 Jul 1394 07:45

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