خاصیت ضد میکروبی عصاره عسل

عنوان انگليسی

Antimicrobial Activity of Special Propolis Extract

خلاصه انگلیسی

Background & Objectives: Propolis is a hive product that bees manufacture from balsamic resins actively secreted by plants on leaf buds and barks. Propolis composition is highly variable, depending on the plant species and on the season of collection. A special purified Propolis extract (Gh 2002) preparing in a special procedure was examined to evaluate the antibacterial activity against methicillin-susceptible and methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus pyogenes, vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis (VRE) reference strains and clinical isolates. Methods: The microdilution Methods was used to determine minimum inhibitory concentration (MIC) and the minimum bactericidal/microbicidal concentration (MBC). Killing curves were set up to detect the antimicrobial kinetics on MRSA and VRE strains. Results: Special propolis extract had high inhibitory activity against Streptococcus in the range of 0.03-0.06 mg/ml. Most MRSA, VRE strains were inhibited by propolis in the range of 0.125- 0.5 and 0.125- 2 mg/ml of propolis, respectively. Special propolis extract was bactericidal against most MRSA, Streptococcus andVRE in the range of 0.5-1, 0.06-0.25 and 2-> 4 mg/ml, respectively. Special propolis extract (Gh2002) demonstrated concentration-dependent as well as time-dependent antimicrobial activity. Bactericidal activity of special propolis extract was achieved after 4 h of incubation of MRSA and VRE strains. Conclusion: It may be concluded that this special propolis extract is suitable for resistant strains or isolates from patients

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