بررسی اثر درمانی پروپرانولول در کودکان زیر 15 سال مبتلا به همانژیوم

فتحی, افشین and میرزا رحیمی, مهرداد and امامزادگان, رامین and سلیمانی, ندا and امانی, فیروز (1393) بررسی اثر درمانی پروپرانولول در کودکان زیر 15 سال مبتلا به همانژیوم. در: بیست و ششمین همایش بین الکمللی بیماریهای کودکان و دوازدهمین همایش ملی پرستاری کودکان, 24-28 مهرماه 1393, تهران- مرکز طبی کودکان.

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Image - Published Version


Assessment of Propranolol efficacy on pediatric haemangioma

English Abstract

Introduction : Hemangiomas are the most common vascular tumor in infancy. Systemic cortons are the first choice of treatment although they have many side effects. Recent studies show Propranolol efficacy on hemangiomas treatment. It has rapid effect and few side effects. These reasons make us to review its effect. Materials and methods : This interventional study was done on 20 children refer to Bu-Ali hospital. Treatment indications were multiple hemangiomas, organ malfunction and enlarging hemangioma. Treatment on those was started by 1mg/kg/day and increased to 3 mg/kg/day and continued for 6 month. After treatment completion 6 month follow up was done. Results : Patients mean age was 23.15 ± 11.24 month. 65% of them were female and 35% was male. Mean size of lesion was 4.85 ± 3.26 Cm. 70% patients had acceptable respond (more than 50% decrease in size) and 30% had partial respond (less than 50%). This effect is similar to corton effect (about 84%) but with less side effects. In this study there is significant relation between mean lesion size decrease and propranolol usage but no significant relation between size of lesion, age, sex and regression. Conclusion: This study shows that Propranolol has acceptable effect on hemangiomas regression and could be suggested as first choice of hemangimas treatment.

Item Type:Conference or Workshop Item (Speech)
زبان سند : انگلیسی
نویسنده اول :افشین فتحی
نویسنده مسئول :فیروز امانی
کلیدواژه ها (انگلیسی):hemangioma, propranolol , pediatric clinic
Subjects:WA Public Health > WA. 900 Vital Statistics
WA Public Health > WA. 900 Vital Statistics

WS Pediatrics
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
Faculty of Medicine > Department of Basic Sciences > Department of Vital Statistics
ID Code:6029
Deposited By: Dr Firouz Amani
Deposited On:11 Aug 1393 07:39
Last Modified:11 Aug 1393 07:39

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