سمیت سلولی نانوذرات اکسید گادولینیم با پلیمر دی اتیلن گلیکول در رده سلولی ملانومای انسان

بهروزكيا, ژاله and زهدی اقدم, رضا and ریاحی عالم, نادر and رفاهی, سهیلا (1393) سمیت سلولی نانوذرات اکسید گادولینیم با پلیمر دی اتیلن گلیکول در رده سلولی ملانومای انسان. Research Journal of Pharmaceutical, Biological and Chemical Sciences ــ 6 (1). pp. 906-913. شاپا 0975-8585

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In Vitro Cytotoxicity of Gd2O3 Nanoparticles with Diethylene Glycol Polymer in human melanoma Cell Line

English Abstract

Nanoparticles are exceptional in that their physical and chemical properties enable many promising medicinal applications. It is widely accepted that nanoparticles should be thoroughly tested for health hazards or nanotoxicity. The purpose of this study was to assess in vitro cytotoxicity of Gadolinium oxide nanoparticles in Human melanoma Cell Line. The effects of magnetic nanoparticles on this cell were evaluated by light microscopy and by standard cytotoxicity assays. Our results demonstrate a concentration-dependent toxicity for all types of particles tested. Our results suggest that this cell lines provides valuable models to assess the cytotoxicity of nanoparticles in human melanoma Cell Line in vitro.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :ژاله بهروزكيا
نویسنده مسئول :رضا زهدی اقدم
نویسنده :نادر ریاحی عالم
نویسنده :سهیلا رفاهی
Additional Information:Indexed and Abstracted in:ESCI,Scopus, Embase (Elsevier) SCIMAGO, CAS, DOAJ, CABI, Google Scholar, Open J-Gate, Biblioteca, Science Central, Index Scholar AYUSH Research Portal
کلیدواژه ها (انگلیسی):Nanoparticles , Cytotoxicity , Cell line , Gadolinium oxide , Diethylene glycol
Subjects:QV pharmacology > QV 778 Pharmaceutical Nanotechnology
QU Biochemistry
QV pharmacology
QZ Pathology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Medical Physics
ID Code:6331
Deposited By: Dr Soheila Refahi
Deposited On:07 Nov 1393 05:46
Last Modified:06 Apr 1397 08:36

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