ارزیابی بیماری اتوایمیون تیروئید در ملاسما

رستمی مقدم, مجید and ملکی, نصراله and ایرانپرور, منوچهر and صفوی اردبیلی, نسترن and عابد کوهی, سلما (1394) ارزیابی بیماری اتوایمیون تیروئید در ملاسما. Journal of Cosmetic Dermatology ــ 14 (2). pp. 167-171. شاپا 1473-2165

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/jocd.12...


Evaluation of autoimmune thyroid disease in melasma

English Abstract

Melasma is one of the most frequently acquired hyperpigmentation disorders clinically characterized by symmetrical brown patches on sun-exposed areas. To date, few studies have been conducted about the relationship between thyroid autoimmun-ity and melasma. To evaluate the thyroid dysfunction and autoimmunity in nonpregnant women with melasma. A total of 70 women with melasma and 70 age-matched healthy women with no history of melasma were enrolled in the study. We studied the thyroid hormone profile in both groups. The statistical analysis was performed using SPSS software. Patients with melasma had 18.5% frequency of thyroid disorders, and 15.7% had positive anti-TPO, while subjects from the control group had a 4.3% frequency of thyroid abnormalities, and only 5.7% had positive anti-TPO. There was a significantly higher prevalence of thyroid dysfunction in women with melasma compared with control group (P = 0.008). This study suggests that there is a relationship between thyroid autoimmunity and melasma. However, to make recommendations on screening for thyroid disease in patients with melasma, future research of good methodological quality is needed.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :مجید رستمی مقدم
نویسنده مسئول :نصراله ملکی
نویسنده :منوچهر ایرانپرور
نویسنده :نسترن صفوی اردبیلی
نویسنده :سلما عابد کوهی
Additional Information:Impact Factor(2015) 1.126 Abstracting and Indexing in: Science Citation Index Expanded , Web of Science , MEDLINE/PubMed , EBSCO ,Current Contents, Embase , Index Medicus , (NLM), (Thomson Reuters), VINITI
کلیدواژه ها (انگلیسی):melasma; thyroid function test; autoimmunity
Subjects:WK Endocrine System
WR Dermatology
Divisions:Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
Faculty of Medicine > Department of Dermatology , Psychiatry , Neurology
ID Code:6719
Deposited By: Dr Nasrollah Maleki
Deposited On:20 Mar 1394 04:21
Last Modified:26 Nov 1395 07:25

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