صالح زاده, فرهاد (1394) تب مدیترانه ای فامیلی در ایران. International Journal of Rheumatology ــ 2015 . ص.ص.1-6. شاپا 9260-1687
متن کامل
|
متنی
1MB |
آدرس اینترنتی رسمی : http://www.hindawi.com/journals/ijr/2015/912137/
عنوان انگليسی
Familial Mediterranean Fever in Iran: A Report from FMF Registration Center
خلاصه انگلیسی
Background. FamilialMediterranean fever (FMF) is a periodic AR autoinflammatory disorder.This comprehensive study describes FMF in Iran as a country near Mediterranean area. Materials and Methods. From the country FMF registration center 403 patients according to Tel-Hashomer criteria enrolled this study, 239 patients had MEFV gene mutations analyses. Data, if needed, was analyzed by SPSS v20. Results. 175 patients (43.4%) were female and 228 patients (56.6%) were male.The mean age was 21.3 years. Abdominal pain was in 93.3% patients and 88.1% had fever. Abdominal pain was the main complaint of patients in (49.6%).The mean interval between attacks was 36.5±29.6 days and themean duration of every episodes was 43.3±34.5 hours. 15.1% of patients had positive family history and 12.7% had previous surgery; in 52.3% of patients delay in diagnosis was more than three years. 12 commonMEFVgenemutationswere analyzed, 21.33%were withoutmutations, 39.7% had compound heterozygote, 25.52% showed heterozygous, and 13.38% showed homozygous results. The most common compound genotype wasM694V-V726A (% 10.46) and in alleles M694V (% 20.9) and V726A (% 12.7) were the most frequent mutations, respectively. Conclusion. M694V was the most commonmutation, and themost common compound genotype was M694V-V726A. Our genotype results are similar to Arabs and in some way to Armenians, erysipelas-like skin lesions are not common in this area, and clinical criteria are the preferred methods in diagnosis of FMF
نوع سند : | مقاله |
---|---|
زبان سند : | انگلیسی |
نویسنده مسئول : | فرهاد صالح زاده |
ضریب تاثیر و نمایه مجلات: | Indexed in: Pubmed, Scopus, Chemical Abstract Service, Embase, google scholar,Current Abstracts , Ebsco, ProQuest,Biological Abstracts |
کلیدواژه ها (انگلیسی): | FMF, Iran |
موضوعات : | WI سیستم گوارشی WS بیماریهای کودکان |
بخش های دانشگاهی : | دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی |
کد شناسایی : | 6898 |
ارائه شده توسط : | خانم زینب ایمانی |
ارائه شده در تاریخ : | 08 شهریور 1394 05:58 |
آخرین تغییر : | 08 شهریور 1394 05:58 |
فقط پرسنل کتابخانه صفحه کنترل اسناد