مروری بر پتانسیل تمایز نورونی سلول های بنیادی مشتق از بافت چربی

صالحی, حسین and امیرپور, نوشین and نیاپور, علی and رضوي, شهناز (1394) مروری بر پتانسیل تمایز نورونی سلول های بنیادی مشتق از بافت چربی. Stem Cell Reviews and Reports ــ online . pp. 1-16. شاپا 8943-1550

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Official URL: http://link.springer.com/journal/12015


An Overview of Neural Differentiation Potential of Human Adipose Derived Stem Cells

English Abstract

There is wide interest in application of adult stem cells due to easy to obtain with a minimal patient discomfort, capable of producing cell numbers in large quantities and their immunocompatible properties without restriction by ethical concerns. Among these stem cells, multipotent mesenchymal stem cells (MSCs) from human adipose tissue are considered as an ideal source for various regenerative medicine. In spite of mesodermal origin of human adipose-derived stem cells (hADSCs), these cells have differentiation potential toward mesodermal and non-mesodermal lineages. Up to now, several studies have shown that hADSCs can undergo transdifferentiation and produce cells outside of their lineage, especially into neural cells when they are transferred to a specific cell environment. The purpose of this literature review is to provide an overview of the existing state of knowledge of the differentiation potential of hADSCs, specifically their ability to give rise to neuronal cells. The following review discusses different protocols considered for differentiation of hADSCs to neural cells, the neural markers that are used in each procedure and possible mechanisms that are involved in this differentiation.

Item Type:Article
زبان سند : انگلیسی
نویسنده :حسین صالحی
نویسنده :نوشین امیرپور
نویسنده :علی نیاپور
نویسنده مسئول :شهناز رضوي
Additional Information:Impact Factor (2014) 2.768 Indexed in: Pubmed/Medline/ Index Medicus, SCOPUS, EMBASE, Chemical Abstracts Service, Google Scholar, EBSCO, CSA, Academic OneFile, Academic Search, AGRICOLA, BIOSIS, BIOSIS Review Reports and Meetings, EMBiology, OCLC, SCImago, Summon by ProQuest
کلیدواژه ها (انگلیسی):HADSCs, Potential, Neural differentiation, In vitro, In vivo
Subjects:QS Human Anatomy
QT physiology
QU Biochemistry
WL Nervous system
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Anatomy
ID Code:7106
Deposited By: Dr Ali Niapour
Deposited On:23 Oct 1394 11:19
Last Modified:20 Jan 1397 13:35

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