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اپیدمی در حال ظهور بیماری التهابی روده در یک کشور با درآمد متوسط: یک مطالعه در سراسر کشور ایران

ملک زاده, مسعود ، واحدی, همایون ، گوهری, کیمیا ، مهدی پور, پریناز ، ملک زاده, رضا ، یزدانبد, عباس (1394) اپیدمی در حال ظهور بیماری التهابی روده در یک کشور با درآمد متوسط: یک مطالعه در سراسر کشور ایران. Archives of Iranian Medicine ــ 19 (1). ص.ص.1-15. شاپا 2977-1029

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آدرس اینترنتی رسمی : http://www.aimjournal.ir/article.aspx?id=949


عنوان انگليسی

Emerging Epidemic of Inflammatory Bowel Disease in a Middle Income Country: A Nation-wide Study from Iran

خلاصه انگلیسی

BACKGROUND: The burden of inflammatory bowel disease (IBD) hasn't been reported in Iran. We aimed to estimate the prevalence and incidence of IBD and its trend in Iran at national and subnational level from 1990 to 2012. METHODS: We conducted a systematic review of English and Persian databases about the epidemiology of IBD. We also collected outpatient data from 17 provinces of Iran using almost all public and private referral gastroenterology clinics. Prevalence and incidence rate was calculated at national and subnational levels. The Kriging method was used to extrapolate provinces with missing data and GPR model to calculate time trends of rates at subnational level. RESULTS: We found 16 case series, two population-based studies, and two review articles. We collected 11,000 IBD cases from outpatient databases. Among them, 9,269 (84.26%) had ulcerative colitis (UC), 1,646 (14.96%) had Crohn's disease (CD), and 85 had intermediate colitis (IC). A total of 5,452 (49.56%) patients were male. Mean age at diagnosis was 32.80 years (CI: 13 - 61) for UC and 29.98 years (CI: 11 - 58) for CD. Annual incidences of IBD, UC, and CD in 2012 were 3.11, 2.70, and 0.41 per 100,000 subjects respectively. Prevalence of IBD, UC, and CD in 2012 were 40.67, 35.52, and 5.03 per 100,000 subjects respectively. The incidence of UC and CD showed a significant increase during the study period (P for trend < 0.05). CONCLUSIONS: The incidence and prevalence of IBD are increasing in Iran. Establishing a national IBD registry seems necessary for comprehensive care of IBD patients in Iran.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :مسعود ملک زاده
نویسنده :همایون واحدی
نویسنده :کیمیا گوهری
نویسنده مسئول :رضا ملک زاده
نویسنده :عباس یزدانبد
ضریب تاثیر و نمایه مجلات:Impact Factor: (2014)0.936, Indexed in: ISI, PubMed/MEDLINE, EMBASE, SCOPUS, CINHAL, PASCAL, CSA, SID
کلیدواژه ها (انگلیسی):Crohn’s disease Burden, inflammatory bowel disease, Iran, prevalence, ulcerative colitis
موضوعات :WI سیستم گوارشی
بخش های دانشگاهی :دانشكده پزشكي > گروه داخلی ، قلب ، عفونی
کد شناسایی :7333
ارائه شده توسط : دکتر نصراله ملکی
ارائه شده در تاریخ :26 دی 1394 06:02
آخرین تغییر :26 دی 1394 06:02

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