بررسي دقت تشخيصي وجود آنتي ژن هليكوباكترپيلوري در مدفوع براي تعيين ابتلا به عفونت هليكوباكترپيلوري

علیمحمدی, حسین and پورفرضی, فرهاد and فولادی, نسرین and حاجی جعفری, رضا (1395) بررسي دقت تشخيصي وجود آنتي ژن هليكوباكترپيلوري در مدفوع براي تعيين ابتلا به عفونت هليكوباكترپيلوري. در: The 9th International & 14th National Congress on Quality Improvement in Clinical Laboratories, Apr 19-22, 2016, Tehran- Iran.


Official URL: http://www.iqctehran.ir


Evaluation Study of Helicobacter Pylori Stool Exam Antigen Test in the Diagnosis of Helicobacter Pylori Infection

English Abstract

Background: There are several tests for the detection of H. pylori infection which can be classified as invasive and non-invasive methods. The invasive tests are normally expensive which need endoscopic procedure. It is also not available everywhere, Therefore, there is a need for a quick, inexpensive and reliable non-invasive test to detect H. pylori. This study aimed to evaluate the enzyme immunoassay for the detection of H. pylori antigen in stool in the Ardabil population. Results of tests were compared with gold standard: histology and RUT. Methodology: 60 patients who had been referred to bras clinic by gastroenterologists due to dyspepsia were recruited. The subjects underwent endoscopic examination and twcbiopsies were taken from antrum, the first specimen was used for RUT and the second was used for histology. Meanwhile, a questionnaire was administered and a stool sample were taken and sent for HpSA (Helicobacter pylori Stool Antigen test). Results: If two tests of histology and RUT were positive, patients were considered as H. pylori positive. Thirty patients were positive for H. pylori and equal numbers were negative using gold standard. HpSA was positive in 29 of 30 and negative in 28 of 30. The sensitivity and specificity of the HpSAwere 96.6% and 93.3% respectively. The positive and negative predictive values were 93.5% and 96.5% respectively.

Item Type:Conference or Workshop Item (Poster)
زبان سند : انگلیسی
نویسنده اول :حسین علیمحمدی
نویسنده :فرهاد پورفرضی
نویسنده :نسرین فولادی
کلیدواژه ها (انگلیسی):Helicobacter Pylori, Stool Exam Antigen Test
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:7579
Deposited By: Dr Nasrin Fouladi
Deposited On:26 Feb 1395 07:27
Last Modified:26 Feb 1395 07:27

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