مقایسه فراوانی هیلکوباکترپیلوری در ناحیه کاردیا و دیستال بیماران سرطانی و افراد سالم

فیضی, ایرج and رضازاده, امين and فیضی, فریده and سید حاتمی, احسان (1395) مقایسه فراوانی هیلکوباکترپیلوری در ناحیه کاردیا و دیستال بیماران سرطانی و افراد سالم. International Journal of Advances in Medicine ــ 3 (2). pp. 419-423. شاپا 3925-2349


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Comparison of Helicobacter pylori infection frequency in the cardia and distal esophageal cancer patients with healthy individuals

English Abstract

Background: Helicobacter pylori is a bacterium that detaches from human beings all over the world, i.e., human being is the largest reservoir of this organism. The aim of this study was to investigate the prevalence of infection among patients with esophageal and gastric cardia cancers and healthy people. Methods: This case-control study was done on 144 persons who were divided into two groups (72 persons in each group). The control group included cases with normal endoscopy and the second group involved patients with gastric cardiac and distal esophageal cancer. Patients were sent to a lab to take stool samples. After receiving the lab reports, information was entered in the checklists and then was analyzed via statistical methods using SPSS 19. Results: The percentage of male cases in was 59.7% in case group and 48.6% in control group. The mean age of all patients was 64.2. In the case group 40.3% of patients were smokers and while this percentage was 23.6% in control group. The most common clinical symptom was dyspepsia in 94.4% of the patients. 27.8% of the individuals in the case group and 22.2% of those in control group were with positive gastrointestinal cancer history in family. 45.8% and 54.2% of patients were with cardia and distal esophageal cancer respectively. The incidence of H pylori infection in the case group was 37.5%, which was lower than the control group being 58.3% (p=0.012, OR=0.4, 0.2-0.8). Conclusions: The results showed that Helicobacter pylori infection may play a protective role in the development of esophageal and cardia cancers.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :ایرج فیضی
نویسنده مسئول :امين رضازاده
Additional Information:Indexed in: Index Copernicus
کلیدواژه ها (انگلیسی):Helicobacter pylori, Cardia cancer, Esophageal cancer, Ardabil
Subjects:WO Surgery
Divisions:Faculty of Medicine > Department of Surgery
ID Code:7596
Deposited By: Dr Firouz Amani
Deposited On:27 Feb 1395 10:57
Last Modified:22 Feb 1399 13:51

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