خونریزی مشخص دستگاه گوارش فوقانی در بیماران فوق العاده بدحال

خوشباطن, منوچهر and فرزین, هاله and فتاحی, ابراهیم and انتظاری, مسعود (1386) خونریزی مشخص دستگاه گوارش فوقانی در بیماران فوق العاده بدحال. The Internet Journal of Gastroenterology ــ 5 (2). شاپا 1528-8323

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Significant Upper Gi – Bleeding In Critically Ill Patients

English Abstract

Background: To evaluate risk factors for clinically important upper gastrointestinal bleeding in critically ill patients requiring mechanical ventilation. Methods: In this prospective study, we determined the presence of clinically important gastrointestinal bleeding, evaluated relevant clinical, laboratory, and diagnostic criteria at four University-affiliated intensive care units in Tabriz, Iran. A total of 300 critically ill ICU patients were ventilated for at least 48 hours. Demographic data included patient characteristics and multiple organ dysfunction score. Each day in the ICU, physiologic measurements including multiple organ dysfunction score, feeding, and other drug variable were recorded. Data were analyzed by t-test and mann Whitney test. Results: The significant risk factors for upper gastro intestinal bleeding were low platelet count, maximum serum creatinin, maximum pulmonary component multiple organ dysfunction score, maximum respiratory component multiple organ dysfunction score, maximum cardiac component multiple organ dysfunction score. Conclusions: In critically ill ventilated patients, renal failure respiratory, cardiac dysfunction, and coagulopathy disorder were associated with an increased risk significant gastrointestinal bleeding whereas enteral nutrition and stress ulcer prophylaxis with ranitidine decreased gastrointestinal bleeding.

Item Type:Article
زبان سند : انگلیسی
نویسنده مسئول :منوچهر خوشباطن
کلیدواژه ها (انگلیسی): Upper Gi Bleeding Critically Ill Patient
Subjects:WI Digestive System
Divisions:Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
ID Code:777
Deposited By: Dr Masood Entezariasl
Deposited On:29 Oct 1388 04:38
Last Modified:01 Jun 1391 12:00

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