ارتباط بین اچ پایلوری و پره اکلامپسی در بین زنان باردار

کهنمویی, فریبا and پورفرضی, فرهاد and اسلام نژاد, خدیجه (1395) ارتباط بین اچ پایلوری و پره اکلامپسی در بین زنان باردار. International Journal of Scientific Reports ــ 2 (12). pp. 300-303. شاپا 2454-2164


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Relationship between Helicobacter pylori infection and pre-eclampsia among pregnant women in Ardabil

English Abstract

Background: Studies have shown that certain infections can increase the risk of pre-eclampsia which one of the common infections among pregnant women was H. pylori with prevalence rate of 60-70% in developing countries. The aim of this study was to investigate the association between H. pylori infection and pre-eclampsia among pregnant women. Methods: Blood and stool samples were taken from 108 women with pre-eclampsia and 108 healthy pregnant women. Blood samples analyzed by ELISA for specific antibodies against H. pylori cytotoxin associated gene A (Cag A) antigen and stool samples were studied in terms of the presence of H. pylori Cag A antigen. Collected data were analyzed using statistical methods in SPSS.20. Results: 30 cases (27.8%) of pre-eclampsia women and 34 (31.5%) of healthy women were sero-positive for Cag A antibodies that was not statistically significant difference. Whereas, 67 cases (62.4%) in the case group and 48 cases (44.4%) in the control group had Cag A antigen in stool samples that was statistically significant difference. Conclusions: Results showed that, based on detection of H. pylori antigen in stool samples, frequency of active H. pylori in women with pre-eclampsia was 1.8 times higher than the healthy women.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :فریبا کهنمویی
نویسنده :فرهاد پورفرضی
نویسنده مسئول :خدیجه اسلام نژاد
Additional Information:Indexed in: Index Copernicus
کلیدواژه ها (انگلیسی):Pre-eclampsia, Helicobacter pylori, Cag A
Subjects:WP Gynecology
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
Faculty of Medicine > Department of Anesthesiology , Obstetrics & Gynecology
ID Code:8207
Deposited By: Dr Firouz Amani
Deposited On:15 Sep 1395 08:43
Last Modified:23 Feb 1399 11:08

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