تاثیر استازولامید روی خونریزی داخل مغزی در بیماران باسکته مغزی

عباسی, وحید and سلیمی, مریم and امانی, فیروز (1395) تاثیر استازولامید روی خونریزی داخل مغزی در بیماران باسکته مغزی. International Journal of Advances in Medicine ــ 4 (1). pp. 148-151. شاپا 2349-3925


Official URL: http://www.ijmedicine.com


The effect of acetazolamide on intracerebral hemorrhage in stoke patients

English Abstract

Background: 10-20% of all strokes are caused by intracerebral haemorrhage which is the world's leading cause of neural tube defects and the second cause of mortality in the world. The aim of this study was to assessment the effect of acetazolamide in the symptom improvement, decreasing rankin scale and mortality rate in patients with intracerebral haemorrhage. Methods: This is a clinical trial study that has been done on 120 stroke patients which divided randomly in two groups each with 60 patients. Patients in intervention group take acetazolamide 750 mg/day and in control group take placebo. The status of patients investigated by Rankin scale in three times baseline, 72 hours and 3 weeks after Cerebral haemorrhage. Results: Of all patients, 49 (40.8%) were male and 71 (59.1%) were female. Putamen haemorrhage is the most location for cerebral haemorrhage (n = 43, 35.8%). According to the Rankin scale, 53 (44.2%) of patients were in the status 4 “moderately severe disability. Unable to attend to own bodily needs without assistance and unable to walk unassisted” in baseline. In the intervention group based on Rankin scale after 72 hour and three week the recovery rate was significantly more than control group. Conclusions: Acetazolamide can be effective in treatment haemorrhagic stroke, decreasing Rankin scale and mortality rate in patients with cerebral haemorrhage.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :وحید عباسی
نویسنده :مریم سلیمی
نویسنده مسئول :فیروز امانی
Additional Information:Indexed in: Index Copernicus
کلیدواژه ها (انگلیسی):Acetazolamide, Cerebral haemorrhage, Rankin scale
Subjects:WL Nervous system
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
Faculty of Medicine > Department of Surgery
ID Code:8470
Deposited By: Dr Firouz Amani
Deposited On:09 Nov 1395 11:20
Last Modified:21 Feb 1399 16:17

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