ادهم, داود ، عباسقلی زاده, ناطق ، اباذری, مالک (1395) شناسایی عوامل موثر بر بقا با استفاده از مدل جنگل تصادفی بقا. Asian Pacific Journal of Cancer Prevention ــ 18 (1). ص.ص.129-134. شاپا 1513-7368
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آدرس اینترنتی رسمی : http://journal.waocp.org
عنوان انگليسی
Prognostic Factors for Survival in Patients with Gastric Cancerusing a Random Survival Forest
خلاصه انگلیسی
Background: Gastric cancer is the fifth most common cancer and the third top cause of cancer related death with about 1 million new cases and 700,000 deaths in 2012. The aim of this investigation was to identify important factors for outcome using a random survival forest (RSF) approach. Materials and Methods: Data were collected from 128 gastric ancer patients through a historical cohort study in Hamedan-Iran from 2007 to 2013. The event under consideration was death due to gastric cancer. The random survival forest model in R software was applied to determine the key factors affecting survival. Four split criteria were used to determine importance of the variables in the model including log-rank,conversation?? of events, log-rank score, and randomization. Efficiency of the model was confirmed in terms of Harrell’s concordance index. Results: The mean age of diagnosis was 63 ±12.57 and mean and median survival times were 15.2 (95%CI: 13.3, 17.0) and 12.3 (95%CI: 11.0, 13.4) months, respectively. The one-year, two-year, and three-year rates for survival were 51%, 13%, and 5%, respectively. Each RSF approach showed a slightly different ranking order. Very important covariates in nearly all the 4 RSF approaches were metastatic status, age at diagnosis and tumor size. The performance of each RSF approach was in the range of 0.29-0.32 and the best error rate was obtained by the log-rank splitting rule; second, third, and fourth ranks were log-rank score, conservation of events, and the random splitting rule, respectively. Conclusion: Low survival rate of gastric cancer patients is an indication of absence of a screening program for early diagnosis of the disease. Timely diagnosis in early phases increases survival and decreases mortality.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | داود ادهم |
نویسنده : | ناطق عباسقلی زاده |
نویسنده مسئول : | مالک اباذری |
ضریب تاثیر و نمایه مجلات: | Indexed in: Pubmed/Medline/Undex Medicus, Scopus, Index Copernicus, EMBASE , DOAJ |
کلیدواژه ها (انگلیسی): | Gastric cancer- random survival forest- Hamadan-Iran |
موضوعات : | WA بهداشت عمومي > WA. 900 آمار حياتي WA بهداشت عمومي > WA. 900 آمار حياتي WA بهداشت عمومي WA بهداشت عمومي |
بخش های دانشگاهی : | دانشکده بهداشت > مدیریت سلامت دانشکده بهداشت > گروه آمار دانشکده بهداشت > گروه بهداشت عمومی دانشکده بهداشت > گروه بهداشت عمومی دانشکده بهداشت > گروه بهداشت عمومی |
کد شناسایی : | 8586 |
ارائه شده توسط : | آقای مالک اباذری |
ارائه شده در تاریخ : | 08 فروردین 1396 04:37 |
آخرین تغییر : | 26 فروردین 1397 11:07 |
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