ارزیابی سطح سرمی روی در بیماران مبتلا به ویتیلیگو

رستمی مقدم, مجید and صفوی اردبیلی, نسترن and ملکی, نصراله and چینی فروش, میرمهدی and ملکی فرد, الهام (1396) ارزیابی سطح سرمی روی در بیماران مبتلا به ویتیلیگو. Postępy Dermatologii i Alergologii ــ 34 (2). pp. 116-119. شاپا 1642-395X


Official URL: https://www.termedia.pl/Journal/Advances_in_Dermat...

Persian Abstract

ارزیابی سطح سرمی روی در بیماران مبتلا به ویتیلیگو


Evaluation of the serum zinc level in patients with vitiligo

English Abstract

Introduction: Vitiligo is an acquired, idiopathic disorder characterized by circumscribed depigmented macules and patches, which affects approximately 0.1–2% of the general population worldwide. Zinc is an essential trace element that is necessary for growth and development at all stages of life. Some studies have reported an association between serum zinc levels and vitiligo. Aim: To measure the serum zinc level in patients with vitiligo compared to healthy subjects. Material and methods: One hundred patients with vitiligo and 100 healthy controls were referred to our clinic. The two groups were matched for age and sex. Atomic absorption spectrophotometry was used to measure serum zinc levels. The statistical analysis was performed using SPSS software. Results: The mean serum level of zinc in vitiligo patients and controls was 80.11 ±17.10 µg/dl and 96.10 ±16.16 µg/dl, respectively. The serum zinc level in patients with vitiligo was significantly lower than in healthy controls (p = 0.0001). Conclusions: The results of our study revealed a significant association between vitiligo and serum zinc levels. A relative decrease in the serum zinc level in vitiligo patients can highlight the role of zinc in the pathogenesis of vitiligo, and large-scale studies need to be conducted to confirm these findings and assess the effect of oral zinc supplements in patients with low zinc levels. keywords: vitiligo, serum level, zinc

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :مجید رستمی مقدم
نویسنده مسئول :نصراله ملکی
نویسنده :میرمهدی چینی فروش
Additional Information:Impact Factor (2015) 1.342 Indexed in: ISI, Pubmed, Scopus, Academic Search Complete, Bielefeld Academic Search Engine,EBSCO, DOAJ, EMBASE, Free MedicalProQuest Journals, HINARI, Index Copernicus,
کلیدواژه ها (انگلیسی):vitiligo, serum level, zinc
Subjects:WR Dermatology
Divisions:Faculty of Medicine > Department of Dermatology , Psychiatry , Neurology
ID Code:8637
Deposited By: Dr Majid Rostami
Deposited On:29 Jan 1396 07:21
Last Modified:29 Jan 1396 07:21

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