اندازه گیري سطح خونی مارکرهاي3 -CEA, CA27-29, CA15در بیماران باسرطان پستان

Title

Measuring of CEA, CA15-3 and CA27-29 Markers in Breast Cancer Patients

English Abstract

Background: This study measured blood level of CEA, CA15-3, and CA27-29 markers in different stages of Breast cancer to determine significant relationship between stage of Breast cancer and blood markers. Material and methods: The present study sectional study was studied 180 patients suffered from breast cancer. Results: In this present study 57.8%of patients were studied because of mass and 52.8% because of micro-calcification in mammography. %25 of patients had positive Family history. Patients in this study were all present in every stages of breast cancer. The pathology of 70% of patients had ductal carcinoma and the rest were from different kinds. 10/5% of patients had metastatic tumor. Significant relation was found between serum Levels of CEA, CA15-3 and stages of breast cancer (p= 0/001, p= 0/0001 respectively). No significant relationship between serum level of CA27-29 and different stages of breast cancer was found. Discussion: Significant and positive relation was found between serum levels of CEA, CA15-3 with different stages of breast cancer. Also, there wasn’t a significant relation between serum level of CA27-29 and different stages of breast cancer. The results were considered that we can use CAE and CA15-3 for predicting and evaluating of breast cancer.Although, because of 70% sensitivity of CA15-3 and 50% of CEA using other diagnostic methods seemed obligatory.

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