ارتباط ABCD2 و سطح خونی BNP در بیماران ایسکیمی گذرای مغزی و سکته مغزی

مرتضی بیگی, حمیدرضا and تقی زاده, اقدس and طالبی, مهناز and امینی, کیوان and گلدوست, محمد (1392) ارتباط ABCD2 و سطح خونی BNP در بیماران ایسکیمی گذرای مغزی و سکته مغزی. Pakistan Journal of Biological Sciences ــ 16 (21). pp. 1393-1397. شاپا 1028-8880


Official URL: http://scialert.net/jindex.php?issn=1028-8880


ABCD2 Score and BNP Level in Patients with TIA and Cerebral Stroke

English Abstract

Abstract: Scoring systems have been designed to help physicians in early prediction of cerebral stroke following Transitional Ischemic Attack (TIA). ABCD2 system is one of these scoring systems. Considering increase of brain natriuretic peptide following cerebral ischemic stroke, BNP level may be associated with incidence of ischemic stroke following TIA. The present study evaluates ABCD2 score, BNP level in patients with TIA and incidence of cerebral stroke. This cross sectional-analytical study evaluated 78 patients with TIA. ABCD2 score was calculated for all patients based on some criteria including age, blood pressure, clinical manifestations (speech/motor disorder), symptoms duration and diabetes. BNP level was measured at the reference laboratory when the patient referred to the treatment center. The patients were followed up for 6 months considering incidence of cerebral stroke and TIA. Mean age of the patients was 66.53±13.08 years and the sample was consisted of 62.8% male and 37.2% female patients. Mean BNP level and mean ABCD2 score was 611.31±125.61 and 4.61±0.99 in all patients, respectively. During follow-up period, TIA recurrence and cerebral stroke were, respectively seen in 11.5 and 3.8% of cases. Mortality was reported in 5.1% of the patients. BNP was significantly higher in cases with recursive TIA (p = 0.03). But, there was not any difference considering ABCD2 score (p = 0.38). BNP is capable of predicting TIA recurrence following first TIA and it can be used in this case.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :حمیدرضا مرتضی بیگی
نویسنده :کیوان امینی
نویسنده مسئول :محمد گلدوست
Additional Information:Indexed in:Pubmed/Medline/Index Medicus, Scopus, Chemical Abstracts, Google Scholar , CABI , Directory of Open Access Journals
کلیدواژه ها (انگلیسی):Transitional Ischemic Attack (TIA),Stroke, ABCD2, brain natriuretic peptide (BNP)
Subjects:WL Nervous system
Divisions:Faculty of Medicine > Department of Internal Medicine , Cardiology , Infectious
ID Code:8689
Deposited By: Ms Zeynab Imani
Deposited On:12 Feb 1396 08:01
Last Modified:10 Apr 1398 11:09

Repository Staff Only: item control page

Document Downloads

More statistics for this item...