نقش گلیکاسیون در توده ای شدن پروتئین

تقوی, فرشته and حبیبی رضایی, مهران and امانی, مجتبی and صبوری, علی اکبر and موسوی موحدی, علی اکبر (1396) نقش گلیکاسیون در توده ای شدن پروتئین. International journal of biological macromolecules ــ 100 . pp. 67-74. شاپا 8130-0141

This is the latest version of this item.

[img] Text
محدود به Repository staff only


Official URL: http://www.sciencedirect.com/science/journal/01418...


The status of glycation in protein aggregation

English Abstract

Protein crucial function and flexibility directly depend on its whole structure which is determined by the native distribution of structural elements. Any disturbances in a protein architecture leads to many kind of abnormalities and intra- or extracellular accumulation of misfolded proteins which are the basis of conformational diseases. Glycation is one of the most important unwanted post-translational modi- fications (PTM) which modifies protein three dimensional decoration and triggers its abnormalities. In current review, we take a look at the brief history of protein glycation, its mechanism and kinetics, glycation consequences and toxic products and its involvement in protein chemical modification, aggregation amyloids and fibril formation and different mechanisms nduced by such alterations

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :فرشته تقوی
نویسنده :مهران حبیبی رضایی
نویسنده :مجتبی امانی
نویسنده :علی اکبر صبوری
نویسنده مسئول :علی اکبر موسوی موحدی
Additional Information:Impact Factor (2015) 3.138 Indexed in: ISI,Pubmed/Medline/Index Medicus, Scopus, Elsevier BIOBASE, Current Contents, EMBASE, FSTA, Polymer Contents, EMBiology, *Review
کلیدواژه ها (انگلیسی):Glycation ,Oxidative stress, Aggregation, Amyloid, Non amyloid
Subjects:QU Biochemistry
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Biochemistry
ID Code:8759
Deposited By: Dr Mojtaba Amani
Deposited On:02 Mar 1396 09:16
Last Modified:02 Mar 1396 09:24

Available Versions of this Item

  • نقش گلیکاسیون در توده ای شدن پروتئین. (deposited 02 Mar 1396 09:16) [Currently Displayed]

Repository Staff Only: item control page

Document Downloads

More statistics for this item...