واسکولیت اولیه مغزی، تجربه ده ساله در کلینیک روماتولوژی کودکان

احمدآبادی, فرزاد and براک, منوچهر and صالح زاده, فرهاد (1396) واسکولیت اولیه مغزی، تجربه ده ساله در کلینیک روماتولوژی کودکان. EC Paediatrics ــ 4 (2). pp. 49-55.


Official URL: https://www.ecronicon.com/paediatrics.php


Childhood Primary Angeitis of CNS, Ten Years’ Experience in a Pediatric Rheumatology Clinic

English Abstract

Background: CNS vasculitis in children as a primary ascular inflammatory process is considered a novel clinical problem in pediatric rheumatology clinics. Methods: From 1996 to 2016 at pediatric rheumatology clinic, patients < 18 years of age were included to this study as having childhood primary angeitis of CNS (cPACNS). Including riteria were: clinical diagnosis of primary CNS vasculitis, and MRA findings demonstrating aneurism and or arterial stenosis not attributable to other causes. Results: 22 patients were enrolled with mean age 10 years, (54%) were female. Headache was in (88%) then mental disorder and seizure in (45%) were the most common neurologic symptoms. The mean delayed to diagnosis was 4 years. Fever was in (54%) and ANA in (31%) was positive. 63 %had abnormality in both MCA and ACA (14 patients), whereas PCA showed abnormity in 36% (8 patients). 86 % had normal EEG results. 22% suffered from severe and permanent neurological damage. Conclusion: Since cPACNS is unfamiliar and rare disorder, e recommend that in any patient with unexplained neurologic symptoms such as headache, seizure and mental disorder, CNS vasculitis should be considered as a probable background.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :فرزاد احمدآبادی
نویسنده :منوچهر براک
نویسنده مسئول :فرهاد صالح زاده
Additional Information:Indexed in: Google scholar
کلیدواژه ها (انگلیسی):CNS Vasculitis; CNS Angeitis; Brain MRI; Brain MRA
Subjects:WL Nervous system
WS Pediatrics
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:8793
Deposited By: Ms Zeynab Imani
Deposited On:10 Mar 1396 04:05
Last Modified:10 Mar 1396 04:05

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