" بررسی غیرفعال سازی نوری استرپتوکوکوس موتانس با روش فوتودینامیک تراپی با استفاده ازدوفتوسنسیتیزرمتیلن بلوو ایندوسیانین گرین

ریخته گران, سهند and عجمی, امیر احمد and کیمیایی, سودابه and جعفری, المیرا and خیام, لیلی and رهبر, مهدی and پیرزاده, طاهره (1395) " بررسی غیرفعال سازی نوری استرپتوکوکوس موتانس با روش فوتودینامیک تراپی با استفاده ازدوفتوسنسیتیزرمتیلن بلوو ایندوسیانین گرین. Journal of International Oral Health ــ 8 (7). pp. 747-752. شاپا 0976-7428


Official URL: http://www.jioh.org/article.asp?issn=0976-7428;yea...


Inactivation of Streptococcus mutans Using Photo-activated Disinfection Therapy with Methylene Blue and Indocyanine Green Photosensitizers

English Abstract

Background: Streptococcus mutans is one of the species in the biofilm adjacent to cariogenic lesions. Photo-activated disinfection (PAD) is a new method which reduces cariogenic bacterial without common side effects. The success of PAD depends on the sensitivity of the organism, type of dyes, a dose of dyes, and the depth of emitted laser. In this study, effect of PAD on S. mutans reduction using indocyanine green (ICG) compared with methylene blue was evaluated. Materials and Methods: The standard turbidity (0.5 McFarland) of S. mutans suspension was prepared. Bacterial suspensions were transferred to the wells. Then, samples were subsequently divided into 7 groups. 1: Negative control, 2: Only methylene blue without laser, 3: Only 640 nm laser, 4: PAD by methylene blue, 5: Indocyanine without laser, 6: Only 810 nm laser, and 7: PAD by ICG. Subsequently, the bacterial suspension from each well was cultured, colony counts were determined, and data were analyzed using one-way ANOVA and Tukey's tests (P < 0.05). Results: There was a significant decrease of S. mutans colony counts after PAD using by both methylene blue and ICG photosensitizers. The highest decreased amount belonged to the ICG (PAD group). Methylene blue group (without laser application) also had a significant decrease of S. mutans colony counts (less effective than both PAD groups). Other groups (laser applications alone and ICG dye without laser) showed no significant bacterial reduction. Conclusion: With the parameters of this study PAD by ICG seems to be more effective than PAD by methylene blue, in reducing S. mutans bacteria as etiological factors of dental caries.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :سهند ریخته گران
نویسنده مسئول :لیلی خیام
نویسنده :طاهره پیرزاده
Additional Information:Indexed in: Scopus, Index Copernicus, Google Scholar نوع مقاله: ORIGINAL RESEARCH برگرفته ار طرح تحقیقاتی
کلیدواژه ها (انگلیسی):Photodynamic therapy, photosensitizers, Streptococcus mutans
Subjects:WU Dentistry. Oral surgery
Divisions:Department of Dentistry > Department of Restorative Dentistry
ID Code:8879
Deposited By: دکتر لیلی خیام
Deposited On:26 Sep 1396 12:05
Last Modified:26 Jan 1397 12:52

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