تاثیر منیزیوم بر شیوع آریتمی در بیماران تحت عمل جراجی بای پس کرونری

محمدزاده, علیرضا and توفیقی, فرشاد and جعفری, ناصر (1397) تاثیر منیزیوم بر شیوع آریتمی در بیماران تحت عمل جراجی بای پس کرونری. ANZ Journal of Surgery ــ 88 (6). pp. 612-615. شاپا 1445-2197

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/ans.140...


Effect of magnesium on arrhythmia incidence in patients undergoing coronary artery bypass grafting

English Abstract

Background: Cardiac arrhythmia after coronary artery bypass grafting (CABG) surgery is a common complication of cardiac surgery. The effect of serum magnesium, hypomagnesaemia treatment and prophylactic administration of magnesium in the development and prevention of arrhythmias is controversial and there are many different ideas. This study evaluates the therapeutic effects of magnesium in cardiac arrhythmia after CABG surgery. Methods: The clinical trial enrolled 250 patients who underwent CABG. Based on the initial serum levels of magnesium, patients were divided into two groups: hypomagnesium and normomagnesium. Based on bioethics committee requirements, patients in the hypomagnesium group received magnesium treatments until they attained normal magnesium blood levels. Both groups underwent CABG with normal blood levels of magnesium. After surgery, each group was randomly divided into two subgroups: one subgroup received a bolus dose of magnesium sulphate (30 mg/kg in 5 min) and the other subgroup received a placebo. Subgroups were under observation in the intensive care unit for 3 days and arrhythmias were recorded. Data from all four subgroups were analysed statistically and interpreted. Results: The results of this study showed that the occurrence of arrhythmia was not significantly different among subgroups (P > 0.05). There was no significant relationship between blood levels of magnesium and arrhythmia during the 3 days post-surgery (P > 0.05). Conclusion: The results of this study showed that magnesium sulphate administration did not significantly improve the incidence of arrhythmias in hypo- and normo-magnesium patients after CABG. There was no significant correlation between post-operative serum levels of magnesium and arrhythmia during 3 days.

Item Type:Article
زبان سند : انگلیسی
نویسنده مسئول :علیرضا محمدزاده
نویسنده :فرشاد توفیقی
نویسنده :ناصر جعفری
Additional Information:IF: 1.605 Indexed in: ISI, PubMed/Medline, Scopus,
کلیدواژه ها (انگلیسی):arrhythmia, coronary artery bypass grafting, hypomagnesaemia, magnesium sulphate.
Subjects:WO Surgery
Divisions:Faculty of Medicine > Department of Surgery
ID Code:8901
Deposited By: Dr Alireza Mohammadzadeh
Deposited On:25 Mar 1396 06:25
Last Modified:16 Nov 1399 08:44

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