title

مقایسه اثر اندانسترون و متوکلوپیرامید در کاهش تهوع و استفراغ بعد از کله سیستکتومی لاپاروسکوپیک

عیسی زاده فر, خاطره and انتظاری, مسعود and شهباززادگان, بیتا and نورانی, زهرا and شفائی خانقاه, یوسف (1396) مقایسه اثر اندانسترون و متوکلوپیرامید در کاهش تهوع و استفراغ بعد از کله سیستکتومی لاپاروسکوپیک. Acta Medica Iranica ــ 55 (4). pp. 254-258. شاپا 0044-6025

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Title

The Comparative Study of Ondansetron and Metoclopramide Effects in Reducing Nausea and Vomiting After Laparoscopic Cholecystectomy

English Abstract

Abstract- Postoperative nausea and vomiting (PONV) are one of the most common complications of anesthesia and without prophylactic intervention occurs by about one-third of patients under general anesthesia. The aim of this study was to compare the efficacy of ondansetron and metoclopramide in reducing PONV after laparoscopic cholecystectomy. In this study, 60 patients undergoing laparoscopic cholecystectomy were randomly allocated into two equal groups (n=30), and in the first group 10 mg metoclopramide and in the second group 4 mg ondansetron preoperatively were injected. Nausea and vomiting and the need for rescue antiemetic treatment in recovery and 6 hr. and 6-24 hrs. After surgery were evaluated. Data were analyzed by SPSS software with chi-square test and analysis of variance (ANOVA).The incidence of nausea in metoclopramide was 43.3 % and in ondansetron was 33.3 %. The difference between two groups was not significant (P=0.6). The incidence of vomiting in metoclopramide was 20% and in ondansetron was 26.7%, and there was not any significant difference between intervention groups (P=0.12). For prevention of PONV after laparoscopic cholecystectomy, both metoclopramide and ondansetron are effective, and in preventing of nausea, ondansetron is more effective than metoclopramide, whereas there was not any significant difference between two drugs in preventing of vomiting

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :خاطره عیسی زاده فر
نویسنده :مسعود انتظاری
نویسنده :بیتا شهباززادگان
نویسنده مسئول :یوسف شفائی خانقاه
Additional Information:Indexed in: Pubmed/Medline/Index Medicus, Scopus, Chemical Abstracts , CAB Abstracts Database, Index Copernicus , Index Medicus for the WHO EMR (IMEMR) , DOAJ, Current Abstracts, Google Scholar , SID, Magiran , Iranmedex , EMRmedex, ISC, Open J-Gate, Abstracts on Hygiene and Communicable Diseases , Protozoological Abstracts , Review of Medical and Veterinary Entomology برگرفته از پایان نامه
کلیدواژه ها (انگلیسی):Ondansetron; Metoclopramide; Laparoscopic cholecystectomy; PONV
Subjects:WO Surgery
Divisions:Faculty of Medicine > Educational Development Office
Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:8935
Deposited By: دکتر بیتا شهباززادگان
Deposited On:20 Apr 1396 04:21
Last Modified:21 Jan 1397 14:45

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