title

بررسی آزمایشگاهی اثر توام پرتو مایکروویو و گرما بر بیان ژن و پارامترهای اسپرم در موش سوری

گوهری, فائزه ، سرانجام, بهزاد ، عسگری, محسن ، امیدی, لیلا ، اکرامی, حمید ، موسوی نجارکلا, سیدعلی (1396) بررسی آزمایشگاهی اثر توام پرتو مایکروویو و گرما بر بیان ژن و پارامترهای اسپرم در موش سوری. Journal of Human Reproductive Sciences ــ 10 (2). ص.ص.128-134. شاپا 0974-1208

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آدرس اینترنتی رسمی : http://www.jhrsonline.org/article.asp?issn=0974-12...


عنوان انگليسی

An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice

خلاصه انگلیسی

Objectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group. Aims: The objectives of this research were to determine the effects of separate and combined exposure to 900-MHz MW (as representative of cell phone radiation) and heat on gene expression and spermogram of male mice. Settings and Design: This experimental animal study was conducted in the school of public health. Materials and Methods: The study was done on 12 male mice randomly divided into four groups (21–23 g): control, test group 1 with separate exposure to 900-MHz MW, test group 2 with separate exposure to hot and sultry climate, and test group 3 with simultaneous whole body exposures to 900-MHz MW and hot and sultry climate. In all studied groups, gene expression and sperm parameters were measured. Results: Tissue samples in all test groups showed integrity of the seminiferous tubule followed by all types of germ line cells. Significant increases in the number of dead sperms in mice with separate exposure to heat were observed in comparison with the other studied groups (P < 0.05). The ratio of Bax expression was elevated to 0.015 ± 0.006 in mice after combined exposures to 900-MHz MW and heat. Conclusion: Separate and combined exposure to 900-MHz MW and heat may induce adverse effects on sperm parameters and gene expression of studied male mice.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :فائزه گوهری
نویسنده :بهزاد سرانجام
نویسنده مسئول :سیدعلی موسوی نجارکلا
ضریب تاثیر و نمایه مجلات:Indexed in: Pubmed, Scopus, DOAJ, EMBASE/ Excerpta Medica, Index Copernicus, Indian Science Abstracts
کلیدواژه ها (انگلیسی):Combined exposure, gene expression, heat, microwave, sperm parameters
موضوعات :WN پرتو شناسی
بخش های دانشگاهی :دانشکده بهداشت > گروه بهداشت حرفه ای
کد شناسایی :9126
ارائه شده توسط : آقای بهزاد سرانجام
ارائه شده در تاریخ :19 شهریور 1396 07:27
آخرین تغییر :19 شهریور 1396 07:27

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