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مقایسه‏ اثرات افزودن میدازولام به بوپیواکایین در بی‏حسی اسپاینال

عیسی زاده فر, خاطره ، انتظاری, مسعود ، علی اکبری, زهرا (1396) مقایسه‏ اثرات افزودن میدازولام به بوپیواکایین در بی‏حسی اسپاینال. Journal of Advances in Medicine and Medical Research ــ 24 (8). ص.ص.1-7. شاپا 2456-8899

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آدرس اینترنتی رسمی : http://www.sciencedomain.org/abstract/22038


عنوان انگليسی

The effects of adding intrathecal midazolam to bupivacaine in spinal anesthesia

خلاصه انگلیسی

Aim:To study of intrathecal bupivacaine with and without midazolam to assess its effect on the onset, duration of sensory and motor block in lower limb surgery. Materials and methods: Eighty patients were randomly allocated to two groups: 40 patients in the control group received 3 ml of 0.5% bupivacaine plus 0.4 ml of 0.9% saline intrathecally; 40 patients in the midazolam group received 3ml of 0.5% bupivacaine plus 0.4 ml (2mg) midazolam. The onset, duration of sensory/motor block, side effects, sedation score and time for request for first rescue analgesia were noted in two groups. Data collected by questionnaires and the data were extracted and analyzed by SPSS software with Ch-square and T-tests. Results: There was not significantly deference in onset of sensory and motor block between the groups (p>0.05). The duration of sensory and motor block was prolonged in the midazolam group significantly (p-value =0.005, p-value = 0.014 respectively). There were no episodes of hypotension, bradycardia, pruritus, vomiting and urinary retention in any patients. Incidence of nausea and sedation score was comparable in the two group. Sedation score in the Midazolam group (3 patient had grade 1 sedation , 35 patients had grade 2 sedation and 2 patients had grade 3) was slightly higher than control group (1 patient had grade 1 sedation , 32 patients had grade 2 sedation and 7 patients had grade 3) (p=0.05). Request time for first rescue analgesia (Diclofenac) was longer in patients who received midazolam (147.38 versus 215.88, p-value<0.001). Conclusion: Intrathecal midazolam increased the duration of sensory and motor block without increasing side effects.

نوع سند :مقاله
زبان سند : انگلیسی
نویسنده اول :خاطره عیسی زاده فر
نویسنده مسئول :مسعود انتظاری
نویسنده :زهرا علی اکبری
ضریب تاثیر و نمایه مجلات:Indexed in: Index copernicus, Google Scholar برگرفته از پایان نامه
کلیدواژه ها (انگلیسی):: analgesia, bupivacaine, intrathecal midazolam, sensory block.
موضوعات :QV فارماکولوژی
بخش های دانشگاهی :دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی
دانشكده پزشكي > گروه بیهوشی، زنان و زایمان
کد شناسایی :9451
ارائه شده توسط : دکتر خاطره عیسی زاده فر
ارائه شده در تاریخ :13 آذر 1396 07:31
آخرین تغییر :06 شهریور 1397 13:41

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