مقاومت آنتی بیوتیکی هلیکوباکتر پیلوری در کودکان ایران: مطالعه مروری و متا آنالیز

یوسفی اوروند, ارشید and واعظ, حمید and تفقدی, محسن and صاحبکار, امیر حسین and ارزنلو, محسن and خادمی, فرزاد (1396) مقاومت آنتی بیوتیکی هلیکوباکتر پیلوری در کودکان ایران: مطالعه مروری و متا آنالیز. Microbial Drug Resistance ــ 24 (7). pp. 980-986. شاپا 1076-6294

[img] Text
محدود به Repository staff only


Official URL: https://www.liebertpub.com/doi/10.1089/mdr.2017.02...


Antibiotic Resistance of Helicobacter pylori in Iranian Children: A Systematic Review and Meta-Analysis

English Abstract

Antibiotic therapy for children infected with Helicobacter pylori is important. However, resistance to antibiotics is one of the main causes of treatment failure. This study was designed to evaluate the prevalence pattern of antibiotic resistance of H. pylori in Iranian children using a systematic review and meta-analysis of literature. A computerized search (until June 10, 2017) using related keywords in the national and international databases was performed. A total of 261 original articles on antibiotic resistance of H. pylori in Iranian children were collected. After screening for inclusion and exclusion criteria, six eligible articles were included in the meta-analysis. Resistance rates of H. pylori to different antibiotics were as follows: metronidazole: 71%, clarithromycin: 12.2%, amoxicillin: 20.4%, tetracycline: 8.4%, ampicillin: 21.4%, rifampin: 28.6%, furazolidone: 8.4%, ciprofloxacin: 16.2%, azithromycin: 19%, erythromycin: 15.3%, and nitrofurantoin: 0%. The prevalence of H. pylori resistance to metronidazole, amoxicillin, ampicillin, and rifampin among Iranian children was high. Therefore, a careful monitoring of antibiotic resistance to select the best treatment options and prevent treatment failure is required. Although resistance to some antibiotics such as clarithromycin, tetracycline, furazolidone, and ciprofloxacin was less prevalent, frequent consumption of these drugs in children should be controlled owing to their known adverse events.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :ارشید یوسفی اوروند
نویسنده :حمید واعظ
نویسنده :محسن تفقدی
نویسنده :امیر حسین صاحبکار
نویسنده :محسن ارزنلو
نویسنده مسئول :فرزاد خادمی
Additional Information:Impact Factor (2016) 2.306 Indexed in: ISI, PubMed/Medline/Index Medicus, Scopus
کلیدواژه ها (انگلیسی):Helicobacter pylori, antibiotic resistance, children, Iran
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:9626
Deposited By: Dr Farzad Khademi
Deposited On:27 Mar 1397 14:24
Last Modified:26 Oct 1401 10:17

Repository Staff Only: item control page

Document Downloads

More statistics for this item...