مطالعه مروری و متاآنالیز شیوع سودوموناس آئروژینوزای مقاوم به ایمیپنم در ایران

واعظ, حمید and صالحی ابرقوئی, امین and خادمی, فرزاد (1396) مطالعه مروری و متاآنالیز شیوع سودوموناس آئروژینوزای مقاوم به ایمیپنم در ایران. GERMS ــ 7 (2). pp. 86-97. شاپا 2248-2997

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Systematic review and meta-analysis of imipenem-resistant Pseudomonas aeruginosa prevalence in Iran

English Abstract

Introduction Imipenem-resistant Pseudomonas aeruginosa (IRPA), due to resistance to different classes of antibiotics and its remarkable capacity to survive in harsh and adverse conditions such as those in the hospital environment, is considered a serious threat to the healthcare system. Given the great impact of IRPA on patients’ outcome and in order to possibly improve antibiotic prescription, this study was conducted to determine the prevalence of clinical isolates of IRPA in different parts of Iran. Methods A systematic literature search was performed in PubMed, Web of Science, Google Scholar and Scopus, as well as in two Iranian domestic search engines, i.e., Iranian Scientific Information Database and Magiran. Finally, after applying exclusion and inclusion criteria 37 articles with full-texts describing the prevalence of imipenem-resistant P. aeruginosa were selected for meta-analysis and systematic review. Results The pooled estimation of 5227 P. aeruginosa isolates in this analysis showed that the percentage of imipenem-resistant P. aeruginosa is about 54% in the Iranian population (95%CI: 0.47-0.62, logit event rate=0.19, 95%CI: -0.12,0.49). Conclusion The findings of this analysis show that in the majority of Iranian hospitals the relative frequency of IRPA is high, therefore, in order to prevent further dissemination of IRPA, more appropriate antibiotic prescription and infection control policies must be implemented by decision-makers

Item Type:Article
زبان سند : انگلیسی
نویسنده مسئول :حمید واعظ
نویسنده :امین صالحی ابرقوئی
نویسنده :فرزاد خادمی
Additional Information:Indexed in: Scopus, PubMed/PMC, DOAJ, Google Scholar
کلیدواژه ها (انگلیسی):Imipenem-resistant Pseudomonas aeruginosa, carbapenem resistance, Pseudomonas aeruginosa, multidrug resistant Pseudomonas aeruginosa
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:9633
Deposited By: Dr Farzad Khademi
Deposited On:24 Nov 1396 08:25
Last Modified:26 Oct 1401 10:30

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