بررسی اپیدمیولوژیک روی شیوع و الگوی مقاومت آنتی بیوتیکی باکتری های جدا شده از عفونت دستگاه ادراری در مرکز ایران

قنبری, فهیمه and خادمی, فرزاد and صابریان پور, شیرین and شاهین, مجتبی and قنبری, نفیسه and نادری, کوروش and مطلبی راد, طاهره (1396) بررسی اپیدمیولوژیک روی شیوع و الگوی مقاومت آنتی بیوتیکی باکتری های جدا شده از عفونت دستگاه ادراری در مرکز ایران. Avicenna Journal of Clinical Microbiology and Infection ــ 4 (3). pp. 2-5. شاپا 2383-0298


Official URL: http://ajcmicrob.com/en/articles/55371.html


An Epidemiological Study on the Prevalence and Antibiotic Resistance Patterns of Bacteria Isolated from Urinary Tract Infections in Central Iran

English Abstract

Background: Urinary tract infection (UTI) is one of the most common bacterial diseases in outpatients and inpatients worldwide. Treatment of UTI has become challenging due to the emergence of pathogens with increasing resistance to antimicrobial agents. Objectives: The aim of this study was to determine the prevalence and antimicrobial resistance patterns of main bacteria responsible for UTI. Methods: In this study, 326 patients with UTI, referring to Shahid Motahari hospital of Fuladshahr, Iran, were evaluated between March 2015 and February 2016. The isolated bacteria were identified by biochemical tests. Disk diffusion method was applied to determine the antibiotic sensitivity of bacterial agents. Results: In a total of 326 positive urine cultures, 273 (83.74%) and 53 (16.25%) samples belonged to females and males, respectively. The most prevalent isolates were Escherichia coli (58.28%), Klebsiella spp. (11.65%), Staphylococcus spp. (11.65%), Enterobacter spp. (7.05%), Streptococcus spp. (3.68%), Enterococcus spp. (2.45%), Proteus spp. (1.22%), Pseudomonas spp. (0.61%), and Citrobacter spp. (0.61%), respectively. The antimicrobial susceptibility analysis of E. coli, as the predominant cause of UTI, revealed the following results: gentamicin (28.6%), ciprofloxacin (48.4%), nitrofurantoin (12.2%), nalidixic acid (63.7%), trimethoprim/sulfamethoxazole (67.9%), cephalothin (60%), cefotaxime (44.8%), imipenem (9.5%), amikacin (66.7%), and ampicillin (85.3%). Conclusions: According to the present survey, E. coli isolates were the predominant pathogens in UTIs and were more prevalent in women than men. In the present study, the frequency of UTI pathogens was comparable to that reported in previous studies, showing an increasing resistance pattern to commonly prescribed antibiotics.

Item Type:Article
زبان سند : انگلیسی
نویسنده مسئول :فهیمه قنبری
نویسنده :فرزاد خادمی
نویسنده :شیرین صابریان پور
نویسنده :مجتبی شاهین
نویسنده :نفیسه قنبری
نویسنده :کوروش نادری
نویسنده :طاهره مطلبی راد
Additional Information:Indexed in: DOAJ, Google Scholar, Index Copernicus, ISC, SID
کلیدواژه ها (انگلیسی):Urinary Tract Infection; Antimicrobial resistance; E. coli
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:9638
Deposited By: Dr Farzad Khademi
Deposited On:03 Mar 1397 12:11
Last Modified:26 Oct 1401 10:25

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