SCCmec تایپینگ سویه های استافیلوکوکوس اورئوس مقاوم در برابر متی سیلین جدا شده از عفونت های اکتسابی از جامعه و بیمارستان

قنبری, فهیمه and صابریان پور, شیرین and زرکش اصفهانی, فاطمه سادات and قنبری, نفیسه and ترقیان, آزاده and خادمی, فرزاد (1396) SCCmec تایپینگ سویه های استافیلوکوکوس اورئوس مقاوم در برابر متی سیلین جدا شده از عفونت های اکتسابی از جامعه و بیمارستان. Avicenna Journal of Clinical Microbiology and Infection ــ 4 (2). pp. 1-6. شاپا 2383-0298


Official URL: http://ajcmicrob.com/en/articles/13849.html


Staphylococcal Cassette Chromosome mec (SCCmec) Typing of Methicillin-Resistant Staphylococcus aureus Strains Isolated from Community- and Hospital-Acquired Infections

English Abstract

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for the growing number of hospital- and community-acquired infections. Objectives: In this study, we aimed to determine the prevalence of MRSA, its antimicrobial resistance profile, and molecular typing of strains isolated from different infections in Iran. Methods: A total of 100 S. aureus strains were isolated from various clinical specimens from Al-Zahra Hospital of Isfahan, Iran during January-June, 2015. Antimicrobial susceptibility test was performed, using the disk diffusion method. For identifying the MRSA phenotype, oxacillin agar screening was performed. Detection of mecA gene among the isolates was performed via polymerase chain reaction (PCR) using specific primers, followed by multiplex PCR for SCCmec typing of MRSA isolates. Results: In the present study, 54 (54%) isolates were identified as MRSA. Overall, 12 (22.23%) and 42 (77.7%) isolates were obtained from community- and hospital-acquired infections, respectively. SCCmec typing among MRSA isolates showed that 19 (35.18%), 13 (24.07%), 6 (11.11%), 5 (9.25%), and 3 (5.55%) isolates contained SCCmec type III, type I, type IV, type II, and type V, respectively; however, 8 (14.81%) isolates were nontypable. Conclusions: In the current study, SCCmec type III isolates were the most common among 54 MRSA isolates in a teaching hospital in the center of Iran. This finding might be attributed to antibiotic pressure, facilitating clonal selection

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :فهیمه قنبری
نویسنده :شیرین صابریان پور
نویسنده :فاطمه سادات زرکش اصفهانی
نویسنده :نفیسه قنبری
نویسنده :آزاده ترقیان
نویسنده مسئول :فرزاد خادمی
Additional Information:Indexed in: DOAJ, Google Scholar, ISC, SID, Magiran
کلیدواژه ها (انگلیسی):Staphylococcus aureus; SCCmec type; CA-MRSA; HA-MRSA
Subjects:QW Microbiology and Immunology
Divisions:Faculty of Medicine > Department of Basic Sciences > Department of Microbiology
ID Code:9639
Deposited By: Dr Farzad Khademi
Deposited On:06 Dec 1396 11:39
Last Modified:26 Oct 1401 10:33

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