title

مقایسه مقادیر الفاامیلاز وپراکسیدازبزاقی در زنان مبتلا به دیابت بارداری و زنان باردار سالم

زمانی اهری, اولدوز and فلسفی, پریسا and پورعلی بابا, فیروز and اسلامی, حسین and ملکی, صالح and رهبر, مهدی and پاکدل, فرزانه (1395) مقایسه مقادیر الفاامیلاز وپراکسیدازبزاقی در زنان مبتلا به دیابت بارداری و زنان باردار سالم. Biomedical &Pharmacology Journal ــ 9 (2). pp. 499-506. شاپا 0974-6242

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Title

Comparison of Salivary Alpha Amylase and Peroxidase Levels in Women with GDM and Non-Diabetic Pregnant Women

English Abstract

Gestational diabetes is first diagnosed during pregnancy. There are Evidences of increased oxidative stress in pregnant women and on the other hand, the role of oxidative stress and impaired antioxidant system in complications during pregnancy such as premature delivery and miscarriage have been proved. Given that peroxidase as an enzymatic antioxidant and alpha-amylase as salivary enzyme, are important variables associated with diabetes, and regarding contradictory articles about their increase or decrease, assessing both factors in terms of reducing the complications of diabetes. In this cross-sectional study, unstimulated saliva of 31 patients with gestational diabetes and 59 non-diabetic pregnant patients were collected and amounts of salivary peroxidase alpha-amylase were assessed separately in these individuals. Data obtained from the study was statistically analyzed using descriptive statistics methods and Mann-Whitney test. P <0.05 was considered as significant in all tests. The mean value of salivary peroxidase level was -54.55 ± 48.7 in women with gestational diabetes and 24.71 ± 8.77 in non-diabetic pregnant women. The mean value of amylase level in the saliva was 609387.1± 132534.38 in women with gestational diabetes and 478559 ±.8581000.41 in non-diabetic pregnant women. According to the data obtained from this study, it could be stated that in women with gestational diabetes the level of alpha-amylase is increased but the level of salivary peroxidase is reduced, compared with non-diabetic pregnant women, but none of these changes are significant.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :اولدوز زمانی اهری
نویسنده مسئول :فرزانه پاکدل
Additional Information:Indexed in: Scopus, Chemical Abstracts, Googlr Scholar, Index Copernicus
کلیدواژه ها (انگلیسی):alpha-amylase; salivary peroxidase; gestational diabetes mellitus
Subjects:WU Dentistry. Oral surgery
Divisions:Department of Dentistry > Department of Oral Surgery, and Maxillofacial
ID Code:9652
Deposited By: Dr Ulduz Zamani Ahari
Deposited On:30 Oct 1396 11:17
Last Modified:30 Oct 1396 11:17

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