اثر کلامیدیا پنومونیه بر انفارکتوس میوکارد

عنوان انگليسی

Effect of Chlamydia Pneumonia Infection on Myocardial Infarction

خلاصه انگلیسی

Abstract: Athrosclerosis is the major cause of cerberovascular accidents and cardiovascular disease in the world. In USA, 25% of people suffer from atherosclerosis and this phenomenon is cause of 42% of all death. In developing countries such as India, improvement in life standards and socioeconomic levels is accompanied with increase in mortality of cardiovascular disease. Atherosclerosis is a inflammatory disease of vessels and role of numerous risk factors like diabetes, hypertension, hyperlipidemia and cigarette has been proved. However among some individuals with atherosclerosis known risk factors aren't seen. On the other hand despite of numerous attempts in control of metabolic risk factors, mortality rate curve resulted from cardiovascular diseases, have changed to plateau state in the western countries. Furthermore in the America, both mortality induced by chronic disease like atherosclerosis and mortality induced by infectious diseases have inverse relation with outcome and literacy level of persons, and this subject has elicited this hypothesis that there is correlation between environmental factors like infectious diseases and process of atherosclerosis. Relation between myocardial infarction and other factors such as infections has been a matter of interest for rechearchers. Our study was a case-control one and in that, 60 patients with myocardial infarction as case group and 60 non-cardiac patients ,as control group, selected from other wards of Ardabil Bouali Hospital, were evaluated and compared. The data of both groups recorded in a researcher made questionnaire. Serum samples were sent to laboratory to determine the level of anti-Chlamydia IgG antibodies with enzyme immuneassay. Control group patients were matched in age and sex and the same serum test was done for them. In each group, 48 persons (80%) were men and 12 persons (20%) were women. Mean age of patients in case group was 58.83+/-12.6 (SD) and in control group was 59.08+-11.59. All of the patients in both groups had high serum level anti-Chlamydia IgG antibodies (titer great her than 5U ml). The difference of mean IgG level in two groups with t test was not significant (p value 0.85). In this study all of the patients in case and control groups had high serum anti-Chlamydia IgG antibodies that maybe related to cold weather and high population in our area

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