عفونت های باکتریایی با بیماری قلبی عروقی در ایران مرتبط هستند

عنوان انگليسی

Bacterial infections are associated with cardiovascular disease in Iran: a meta analysis

خلاصه انگلیسی

Introduction: The present study aimed to assess the prevalence and associa-tion of various bacterial infections with cardiovascular disease (CVD) in Iran.Material and methods: An electronic search was performed using related keywords in the national and international databases up to June 30, 2017. Out of the 1807 articles found on the associations between bacterial infec-tions and CVD, 20 relevant studies were selected for the meta-analysis.Results: The prevalence of bacterial infections was higher in case groups compared with the control groups. Odds ratios for assessing the association between Chlamydia pneumonia infection and CVD based on PCR, IgG and IgA tests were 7.420 (95% CI: 3.088–17.827), 3.710 (95% CI: 1.361–10.115) and 2.492 (95% CI: 1.305–4.756), respectively. Moreover, the calculated odds ratio for Mycoplasma pneumonia infection was 1.815 (95% CI: 0.973–3.386). For Helicobacter pylori infection, odds ratios based on IgG and IgA tests were 3.160 (95% CI: 1.957–5.102) and 0.643 (95% CI: 0.414–0.999), respectively.Conclusions: The present meta-analysis suggested that there was a signif-icant association between H. pylori, C. pneumonia and M. pneumonia infec-tions and CVD in Iran. These findings confirm the potential role of bacterial infections as predisposing factors for CVD.

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