ترتیبیان, بختیار ، FitzGerald, LZ ، آزادپور, نوشین ، حاجی زاده مالکی, بهزاد (1394) تاثیر ورزش بر سطوح سیتوکین های التهابی در زنان منوپوز-مطالعه کنترل شده تصادفی. Post Reproductive Health ــ 21 (1). ص.ص.9-15. شاپا 2053-3691, 2053-3705
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آدرس اینترنتی رسمی : https://journals.sagepub.com/doi/full/10.1177/2053...
عنوان انگليسی
A randomized controlled study examining the effect of exercise on inflammatory cytokine levels in post-menopausal women
خلاصه انگلیسی
BACKGROUND: Elevated plasma levels of inflammatory cytokine are associated with body mass index, percent body fat and increased morbidity. Evidence suggests that higher levels of physical activity result in beneficial anti-inflammatory effects compared to a more sedentary lifestyle. Further, reproductive hormones are associated with inflammaotry cytokines. This study examined the effect of a 16-week low-moderate intensity exercise (EX) programme on reproductive hormones and inflammatory cytokines. METHODS: Twenty-eight healthy, sedentary post-menopausal women were randomly assigned to EX (n = 14) or control (Con, n = 14) groups. The EX group completed low-moderate intensity treadmill training 25-30 min/day, up to 55% of HRmax, 3-4 days/week, for 16-weeks. Con maintained current physical activity level. Baseline and week-16 serum samples evaluated interleukin-1 beta, interleukin-6, tumor necrosis factor-alpha, C-reactive protein, estradiol, luteinizing hormone and follicular stimulating hormone. RESULTS: Post-intervention, the EX group showed a significant decrease in interleukin-1 beta, interleukin-6, tumor necrosis factor-alpha, estradiol, follicular stimulating hormone and luteinizing hormone levels compared to baseline values. No significant changes were observed in Con. Significant correlations were observed between IL-1β, IL-6, TNF-α, and reproductive hormones, both before and after the exercise intervention. CONCLUSION: Findings suggest that a low-moderate intensity EX programme decreases cytokines in relation to reproductive hormones in post-menopausal women. These findings support the role of EX in reducing inflammatory markers and improved reproductive hormones in post-menopausal women.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | بختیار ترتیبیان |
نویسنده مسئول : | LZ FitzGerald |
نویسنده : | نوشین آزادپور |
نویسنده : | بهزاد حاجی زاده مالکی |
ضریب تاثیر و نمایه مجلات: | Indexed in: PubMed/Medline, Scopus, Embase |
کلیدواژه ها (انگلیسی): | Cytokines; hot flushes; menopause; moderate exercise; sex hormones |
موضوعات : | QT فیزیولوژی WP بیماریهای زنان |
کد شناسایی : | 12509 |
ارائه شده توسط : | خانم نوشین آزادپور |
ارائه شده در تاریخ : | 07 دی 1398 09:05 |
آخرین تغییر : | 07 دی 1398 09:05 |
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