بیومارکرها و سرطانهای شایع دهان: بررسی مطالعات کارازمایی بالینی

عنوان انگليسی

Biomarkers and common oral cancers: Clinical trial studies

خلاصه انگلیسی

Oral cancer (oral squamous cell carcinoma (OSCC)) has been known as the one of the important types of human cancer worldwide. The number of this cancer has been increased in low-income countries and also the therapeutic and diagnostic applications have been improved in recent years. Many studies show that there is a significant relationship between tissue level changes and molecular level which lead to malignant changes and make an important role in disease progress. Biomarkers are widely categorized as metabolomics, proteomics or genomics. Oncology research and molecular biology studies on biomarkers that involved in oral cancer (OC) focus on identification of pivotal biological markers related to cancer progression, risk assessment, predicting recurrence, screening, showing prognosis, demonstrating metastasis/invasion, and monitoring cancer treatment reactions. The aim of this review is evaluating efficiencies and functions of biomarkers in diagnosis, monitoring, prognosis and therapeutic responses of OCs in the recent decade

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