ساخت نانو ذرات Fe2O3@C/PIDA برای تثبیت نانوذرات نقره: نانوساختار مهندسی شده برای فعالیت زیستی و ضد میکروبی

عنوان انگليسی

Fabrication of ?-Fe2O3@C/PIDA nanosphere to stabilize silver nanoparticles: Engineered nanostructure to bioactivity and antimicrobial activity

خلاصه انگلیسی

Bacteria contamination in drinking water and medical products poses serious threats to the environment and public health. Therefore, the design and synthesis of green-based nanostructures to eliminate bacteria contaminants from the aquatic environment have remained a huge challenge for biomedical and environmental purposes. Herein, the fabricated silver nanoparticles (Ag NPs) supported on propyliminodiacetic acid (PIDA)-functionalized gamma-Fe2O3@carbon nanospheres were successfully engineered. The morphology and structure features of the core-shell nanocomposites were investigated with FESEM, TEM, and AFM. From the VSM analysis, the saturation magnetization of the nanocomposite obtained 20.18 emu/g, which provided facile separation of the catalyst from reaction mixtures using an external magnet. The proposed core-shell nanocomposite in this study showed remarkable antibacterial activity in Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The MBC amount for both strains was obtained at 512 mu g/mL. Furthermore, MIC for S. aureus and E. coli was achieved at 128 and 256 mu g/ml, respectively. Meanwhile, the decrease in cell viability was indicated at 21% for the MKN45 cell line after 72 h treatment. This novel nanostructure with excellent antimicrobial activity holds promise in combating public health concerns and provides a new horizon for biomedical and environmental applications.

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