بررسی سرولوژیکی تحت تیپ گروه های H5، H7 و H9 ویروس آنفلوانزای مرغی در جمعیت انسانی

عنوان انگليسی

Serological survey of H5, H7 and H9 subtypes of Avian Influenza Viruses in human population

خلاصه انگلیسی

Influenza viruses are an acute respiratory, highly contagious and zoonotic disease which belong to the Orthomyxoviridae family. The H9 subtype is an avian pathogenic influenza virus that its outbreak frequently occurs in poultry farms of Iran. As well, H5 and H7 subtypes are a highly pathogenic avian influenza subtype which causes high mortality in poultry and wild birds. Some subtypes of influenza viruses can transmit to human from birds and the antigenic shift is common among these viruses. This study was to carried out to determined antibodies to H5, H7 and H9 subtypes of avian influenza virus in different human population related to poultry industry in Ardabil area, northwest of Iran. In this survey, 105 blood samples were collected from poultry vaccinators and clinics, and workers of poultry farms and slaughter-house. Serum samples were examined by HI test for differentiate H5, H7 and H9 subtypes and sera with titers ≥4 (log2) were considered positive. 17.2% with 21.14±10.59 titer from poultry vaccinators and clinics sera and 12.8% with 26.02±11.35 titer from workers of poultry farms and slaughter-house sera were positive for H9N2 influenza virus (HI titers ≥1/20). All tested sera were negative for H5N1, H5N2, H7N1 and H7N7 avian influenza viruses. According to results of this study, different human population related to poultry industry were contacted with H9N2 avian influenza virus that it should be critical during outbreaks of avian influenza subtypes posing a major public thealt.

Document Downloads