اسکندرپور, الناز ، احدی, عادل ، معینی جزنی, آرزو ، نسیمی دوست, رامین ، ملاطفی, رسول (1402) اثر تیموس ولگاریس ، اویشن، در کاهش شدت سرفه بیماران مبتلا به حمله اسم، یک مطالعه کارازمایی بالینی سه سو کور. Allergologia et Immunopathologia ــ 52 (1). ص.ص.9-15. شاپا 0301-0546
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آدرس اینترنتی رسمی : https://all-imm.com/index.php/aei/article/view/964
عنوان انگليسی
Thymus vulgaris ameliorates cough in children with asthma exacerbation: a randomized, triple-blind, placebo-controlled clinical trial
خلاصه انگلیسی
Background: Asthma is one of the most common chronic respiratory diseases with inflammatory involvement and has a high burden worldwide. This study aimed to determine the effect of Thymus vulgaris (TV) on cough in children between 5 and 12 years old with mild to moderate asthma exacerbation. Methods: In this randomized, triple-blind clinical trial, 60 children between the ages of 5 and 12 with asthma exacerbations were randomly divided into two groups. The intervention group (n = 30) was given TV powder at a dose of 20 mg/kg every 8 hours, prepared as syrup, along with routine medical treatment for a week, and the control group (n = 30) received only routine medical treatment with placebo syrup. At the end of the week, clinical and laboratory symptoms, and spirometry data were re-recorded for both groups. Finally, the recorded factors were compared and statistically analyzed. Results: The results showed that after the intervention, activity-induced cough reduced, and difference was statistically significant between the two groups (p = 0.042), but the reduction in wheezing and breathlessness had no statistically significant difference. Spirometry data showed a significant difference in forced expiratory volume in 1 second (FEV1) between the two groups after intervention (p = 0.048), but this difference was not significant in FEV1/FVC (forced vital capacity), peak expiratory flow (PEF), and forced expiratory flow at 25–75% of the vital capacity (FEF25–75%). Conclusion: The results show that TV syrup may be useful as an adjuvant treatment in children with asthma exacerbations.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | الناز اسکندرپور |
نویسنده اول : | عادل احدی |
نویسنده : | آرزو معینی جزنی |
نویسنده : | رامین نسیمی دوست |
نویسنده مسئول : | رسول ملاطفی |
ضریب تاثیر و نمایه مجلات: | IF: 1.8 Indexed in: ISI, PubMed/Medline, Scopus |
کلیدواژه ها (انگلیسی): | Asthma exacerbation; thymus vulgaris; cough; spirometry; breathlessness |
موضوعات : | WF سیستم تنفسی QV فارماکولوژی > QV 766 گیاهان دارویی |
بخش های دانشگاهی : | دانشكده پزشكي > گروه اطفال ، پزشکی اجتماعی معاونت تحقیقات و فناوری > مرکز تحقیقات طب سنتی و آبدرمانی |
کد شناسایی : | 17860 |
ارائه شده توسط : | دکتر عادل احدی |
ارائه شده در تاریخ : | 14 بهمن 1402 09:47 |
آخرین تغییر : | 14 بهمن 1402 09:47 |
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