اندازه گیری غلظت سرمی نیتریک اکسید سنتاز اندوتلیومی در افراد مبتلا به هلیکوباکتر پیلوری

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عنوان انگليسی

Evaluation of serum concentration of eothelium nitric oxide synthase in Helicobacter pylori positive people

خلاصه انگلیسی

Objectives: Endothelium nitric oxide synthase (eNOS) is a type of enzyme which produces a endogenous factor called nitric oxide. NO plays important role in progress of euplastic diseases. In chronic gastritis induced by Helicobacter pylori, the production of NO enhances and damages DNA. The aim of present study is to evaluate eNOS concentration in serum of healthy people and those infected by HP. Methods: The serums and stools of 84 voluntaries were collected which %58.3 of them were women. HP antigen in stool samples and serum concentration of eNOS were determined using proper ELISA kits. Obtained data were analyzed using Excell software. Results: 16.6%, 29.76% and 53.57% of collected samples were equivocal, HP negative and positive respectively. Comparison of serums concentration of eNOS showed that there is no significant change among these three groups. Discussion: As mentioned in results the eNOS serums concentration shows no significant change in HP positive and negative groups. Albeit the other studies showed the significant increase in serum concentration of HP positive patient, this contradiction may arise from race and HP pathogenic slands such as VacA and CagA differences. We propose to conduct a similar study in Ardabil with special regard to pathogenic islands

ویرایش های موجود این سند

• اندازه گیری غلظت سرمی نیتریک اکسید سنتاز اندوتلیومی در افراد مبتلا به هلیکوباکتر پیلوری. (deposited 17 مرداد 1390 10:20) [Currently Displayed]

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