ارتباط بین سطح سرمی ویتامین د و شدت آسم در کودکان 1 تا 15 ساله

احمدآبادی, فرزاد and میرزا رحیمی, مهرداد and براک, منوچهر and احدی, عادل and علیپور, رسول (1393) ارتباط بین سطح سرمی ویتامین د و شدت آسم در کودکان 1 تا 15 ساله. International Journal of Research in Medical Sciences ــ 3 (1). pp. 239-243. شاپا 2320-6012

Text - Published Version

Official URL: http://www.scopemed.org/?mno=173906


The relationship between serum vitamin D level and asthma severity in asthmatic children (aged 1-15 years) in Ardabil, 2012-13

English Abstract

Background: Vitamin D plays an important role in many immune and allergic diseases, and its deficiency is more in areas with low solar radiation. Asthma is a common disease in children of Ardabil city. The present study was designed to evaluate vitamin D levels in asthmatic children in Ardabil. Methods: A total of 100 asthmatic children (40% boys and 60% girls) with a mean age of 5.7 ± 3.46 years (1-15 years) and who visited the Bou-Ali pediatric hospital were included. Vitamin D levels, disease course, IgE levels, and eosinophil counts were evaluated. A group of healthy children was also included to compare vitamin D levels between asthmatic and non-asthmatic children. All data were analyzed by statistical methods in SPSS v.16. Results: The vitamin D levels in asthmatic children were lower than those in the healthy group. Furthermore, the increase in the vitamin D level was significantly associated with lower history of hospitalization (P = 0.02), better response to bronchodilator treatment (P = 0.01), lower IgE level (P = 0.02), and decrease in the mean age of children (P = 0.04). However, no significant association between vitamin D levels and sex (P = 0.08), history of anti-inflammatory drug use (P = 0.78), and eosinophil count (P = 0.08) was observed in asthmatic children. Conclusion: Results showed that vitamin D deficiency was more common in asthmatic than in non-asthmatic children and the level of vitamin D was directly associated with the response of the children to treatment.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :فرزاد احمدآبادی
نویسنده :مهرداد میرزا رحیمی
نویسنده :منوچهر براک
نویسنده مسئول :عادل احدی
نویسنده :رسول علیپور
Additional Information:indexing in: Directory of Open Access Journals (DOAJ) IMSEAR (WHO), Index Copernicus , Google Scholar ,ScopeMed , CrossRef , Index Scholar , Ulrichsweb , Journal Index , Open J-Gate , Directory of Science , eJManager , JournalTOCs
کلیدواژه ها (انگلیسی):Asthma, Vitamin D level, Children, Allergic diseases
Subjects:WF Respiratory System
WS Pediatrics
Divisions:Faculty of Medicine > Department of Pediatrics , Community Medicine
ID Code:6275
Deposited By: Dr Firouz Amani
Deposited On:29 Oct 1393 05:30
Last Modified:29 Oct 1393 05:34

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