مقایسه مقدار آنتی اکسیدان توتال بزاقی در زنان با دیابت بارداری و زنان باردار غیر دیابتیک

زمانی اهری, اولدوز and زمانی اهری, سحر and فریدی آذر, زهرا and فلسفی, پریسا and غنی زاده, میلاد (1396) مقایسه مقدار آنتی اکسیدان توتال بزاقی در زنان با دیابت بارداری و زنان باردار غیر دیابتیک. Journal of Clinical and Experimental Dentistry ــ 9 (11). e1282-e1286. شاپا 1989-5488


Official URL: http://www.medicinaoral.com/odo/volumenes/v9i11/v9...


Comparison of total antioxidant capacity of saliva in women with gestational diabetes mellitus and non-diabetic pregnant women

English Abstract

Abstract Background: Pregnancy is considered a stressful event, results in higher levels of oxidative stress and considerable Changes in physiological and metabolic functions such as gestational diabetes mellitus (GDM). Due to the cumulative effect of antioxidants and considering the controversies in this area, this study was undertaken to investigate the total antioxidant capacity (TAC) of saliva in pregnant women whit gestational diabetes in comparison to nondiabetic pregnant women. Material and Methods: In this cross-sectional study (2015-16), a total of 31 women with a diagnosis of GDM and 59 non-diabetic pregnant women were included in the diabetic and control groups, respectively. Salivary samples were collected by spitting method. When all samples were collected, total antioxidant capacity (TAC) was measured with the use of a commercial kit following the manufacturer’s instructions. Data were analyzed with descriptive statistics and Mann-Whitney test using SPSS 18. Results: Average TAC level in the saliva of women with gestational diabetes was 0.10 ± 0.14, with 0.04 ± 0.11 in non-diabetic pregnant women. Nonparametric Mann-Whitney test showed that this difference was statistically significant (P=0.024). Discussion: Under the limitations of the present study it can be concluded that there is an increase in oxidative stresses during pregnancy, followed by an increase in the total levels of salivary antioxidants to counteract such stresses. Therefore, it is expected that determining the salivary antioxidant levels during pregnancy can be an alternative technique for the early diagnosis of diabetes.

Item Type:Article
زبان سند : انگلیسی
نویسنده اول :اولدوز زمانی اهری
نویسنده مسئول :پریسا فلسفی
Additional Information:Indexed in: Pubmed/PMC, Scopus
کلیدواژه ها (انگلیسی):Gestational diabetes mellitus, pregnancy, saliva, total antioxidant capacity.
Subjects:WU Dentistry. Oral surgery
Divisions:Department of Dentistry > Department of Oral Surgery, and Maxillofacial
ID Code:9448
Deposited By: Dr Ulduz Zamani Ahari
Deposited On:18 Sep 1396 11:12
Last Modified:07 Mar 1398 14:10

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