قبادی مراللو, حسن ، اصلانی, محمدرضا ، حسینیان, عدالت ، فرزانه, اسماعیل (1396) بررسی ارتباط سطح سرمی ناتریورتیک مغزی و اینترلوکین 6 با کیفیت زندگی در بیماران مزمن انسدادی ریوی. در: ERS International Congress 2017, Sep 9-13 , 2017, Milan- Itlay.
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آدرس اینترنتی رسمی : http://erj.ersjournals.com/content/50/suppl_61/PA1...
عنوان انگليسی
The Correlation of Serum Brain Natriuretic Peptide and Interleukin-6 with Quality of Life using COPD assessment test
خلاصه انگلیسی
Background: Serum pro-brain natriuretic peptide (BNP) and interleukin (IL)-6 levels are increased with chronic obstructive pulmonary disease (COPD). The aim of the present study was to examine the levels of pro-BNP and IL-6 in stable COPD patients and the correlation of these markers with health-related quality of life using COPD assessment test (CAT). Method and Materials: Serum pro-BNP and IL-6 levels were measured in 82 patients with stable COPD. Serum pro-BNP levels, serum IL-6 levels, pulmonary function, and O2 saturation (Spo2) were compared according to GOLD stage and CAT score. Additionally, we tested association both pro-BNP and IL-6 with clinical parameters of patients. Results: Plasma IL-6 and pro-BNP levels increased with enhancing disease severity according to the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) classification (P=0.034, P=0.068; respectively). Also, results showed that plasma levels of pro-BNP and IL-6 were higher in patients with high CAT score (P=0.004, P=0.017; respectively). Additionally, there was positive significantly correlation between plasma pro-BNP and IL-6 levels (r= 0.332; P=0.002). Conclusion: The results demonstrated that with the increasing severity of the obstruction in patients with stable COPD, increased both IL-6 and pro-BNP. This increase in inflammatory markers is associated with reduced quality of life and severity of hypoxia. These results suggest that lowering of IL-6 and pro-BNP may be useful in the management of COPD patients.
نوع سند : | موضوع کنفرانس یا کارگاه (پوستر ) |
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زبان سند : | انگلیسی |
نویسنده مسئول : | حسن قبادی مراللو |
نویسنده : | محمدرضا اصلانی |
نویسنده : | عدالت حسینیان |
نویسنده : | اسماعیل فرزانه |
موضوعات : | WF سیستم تنفسی |
بخش های دانشگاهی : | دانشكده پزشكي > گروه داخلی ، قلب ، عفونی |
کد شناسایی : | 9700 |
ارائه شده توسط : | دکتر محمد رضا اصلانی |
ارائه شده در تاریخ : | 02 بهمن 1396 06:14 |
آخرین تغییر : | 02 بهمن 1396 06:14 |
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