اصلانی, محمدرضا ، امانی, مجتبی ، مقدس, فرانک ، قبادی مراللو, حسن (1401) سطوح سرمی آدیپولین و IL-6 در بیماران با مزمن انسدادی ریوی. Advances in Respiratory Medicine ــ 90 (5). ص.ص.391-398. شاپا 2543-6031
متن کامل
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متنی
- نسخه چاپ شده
757kB |
آدرس اینترنتی رسمی : https://www.mdpi.com/2543-6031/90/5/49
عنوان انگليسی
Adipolin and IL-6 Serum Levels in Chronic Obstructive Pulmonary Disease
خلاصه انگلیسی
Objective(s): One of the adipokines that have insulin-sensitizing properties is adipolin, whose reduced levels have been reported in obesity, oxidative stress, and inflammation. The present study investigated serum interleukin-6 (IL-6) and adipolin levels in chronic obstructive pulmonary disease (COPD) patients. Method: A control case study included 60 COPD patients and 30 healthy subjects in the research and measured adipolin and IL-6 serum levels. In addition, serum adipolin levels in COPD patients were assessed according to the GOLD grade. The relationship between serum adipolin levels and study variables were also analyzed. Results: The results showed reduced adipolin levels in COPD patients compared with healthy individuals (p < 0.001). Furthermore, increased levels of IL-6 were evident in the COPD group compared to the control group (p < 0.001). Adipolin serum levels were positively correlated with PFTs and negatively correlated with IL-6 levels. Conclusion: Decreased adipolin levels enhanced disease severity in COPD patients. It seems that the existence of a significant relationship between adipolin and IL-6 may indicate the role of adipolin in the pathophysiology of COPD.
نوع سند : | مقاله |
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زبان سند : | انگلیسی |
نویسنده اول : | محمدرضا اصلانی |
نویسنده : | مجتبی امانی |
نویسنده : | فرانک مقدس |
نویسنده مسئول : | حسن قبادی مراللو |
ضریب تاثیر و نمایه مجلات: | Indexed in: PubMed/Medline, Scopus, ESCI |
کلیدواژه ها (انگلیسی): | adipolin; IL-6; COPD |
موضوعات : | QT فیزیولوژی WF سیستم تنفسی |
بخش های دانشگاهی : | دانشكده پزشكي > گروه علوم پایه > بخش فیزیولوژی |
کد شناسایی : | 16807 |
ارائه شده توسط : | دکتر محمد رضا اصلانی |
ارائه شده در تاریخ : | 10 اسفند 1401 09:39 |
آخرین تغییر : | 26 شهریور 1402 12:15 |
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