پریکاردیت انقباضی مزمن با ادم محیطی

عنوان انگليسی

Chronic constrictive pericarditis with peripheral edema

خلاصه انگلیسی

Constrictive Pericarditis (CP) is a type of diastolic heart fail- ure that occurs because the inelastic pericardium inhibits the filling of the heart. The true population prevalence is unknown, but among those with viral pericarditis, it is estimated to occur in less than 0.5% of cases [1]. Although the causes of CP can be different (idiopathic, post-viral, tuberculosis, post-surgery, radiation-induced, etc). The last end pathological pathway is the development of fibrous thickening or calcification of the pericardium, which leads to pericardial non-compliance [2,3]. A normal pericardium minimally interferes with ventricular expansion at normal cardiac workloads. In CP, pericardial non- compliance creates a stiff ventricular pericardial unit, leading to increased diastolic pressure and a faster rise in ventricular pres- sure for a given venous return. A non-compliant pericardium limits ventricular relaxation and determines ventricular diastol-ic pressure, resulting in high and uniform diastolic pressure in allchambers. Clinically, this presents predominantly as right-sided congestion. Increased pulmonary capillary wedge pressure and decreased cardiac output response to exercise lead to dyspneavand exercise intolerance, although overt pulmonary edema iscless common than typical systolic heart failure.

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